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Updated: Jan 20, 2026

Using a Bipolar Electrode to Create a Temporal Lobe Epilepsy Mouse Model by Electrical Kindling of the Amygdala
Published on: June 29, 2022
Epilepsy Mimicking Affective Disorder in a Patient with Amygdala Enlargement
Jung-Ju Lee1, Kyusik Kang1, Jong-Moo Park1
1Department of Neurology, Nowon Eulji Medical Center, Eulji University College of Medicine, Seoul, Korea.
Abstract:
Affective disorders are commonly associated with epilepsy. Affective symptoms rarely occur concomitantly with seizure occurrence, which can lead to misdiagnosis. Here, we describe a 69-year-old man who experiencedintermittent manifestations of unpleasant mood and aggressive behavior. He had temporal lobe epilepsy with amygdala enlargement. After successful treatment with an antiepileptic drug, hissymptoms resolved. Additionally, the amygdala enlargement decreased when checked at 5 years after treatment. We discuss the clinical characteristics and differential points of the case.
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Enlargement of the Plasma Membrane

