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Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Electroconvulsive Therapy01:30

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early years,...
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein01:20

Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein

Antiepileptic drugs, such as levetiracetam (Keppra) and brivaracetam (Briviact), have emerged as crucial tools in managing epilepsy. These medications exert their therapeutic effects by targeting the synaptic vesicle protein SV2A, a transmembrane glycoprotein primarily found in the brain.
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...
Antiepileptic Drugs: Glutamate Antagonists01:14

Antiepileptic Drugs: Glutamate Antagonists

Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...

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Related Experiment Video

Updated: Jun 26, 2026

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

Self-Management Intervention for Adults with Epilepsy: A Systematic Review.

Seung Ae Kim1, Dong Wook Kim2

  • 1College of Nursing, Ewha Womans University, Seoul, Korea.

Journal of Epilepsy Research
|June 25, 2026
PubMed
Summary

This review of randomized controlled trials (RCTs) on epilepsy self-management interventions found that longer, hybrid approaches combining in-person education with ongoing support improve patient outcomes. Optimal interventions last six months with regular sessions.

Keywords:
AdultsEpilepsyNursing careRandomized controlled trialSelf-management

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Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice
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Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice

Published on: May 16, 2019

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Last Updated: Jun 26, 2026

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice
07:01

Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice

Published on: May 16, 2019

Area of Science:

  • Neurology
  • Evidence-Based Medicine
  • Health Psychology

Background:

  • Epilepsy self-management is crucial for improving patient quality of life and reducing healthcare burden.
  • Existing self-management interventions for adults with epilepsy vary widely in content, delivery, and effectiveness.
  • A systematic review is needed to synthesize evidence from recent randomized controlled trials (RCTs) on epilepsy self-management.

Purpose of the Study:

  • To systematically review RCTs on self-management interventions for adult epilepsy patients.
  • To analyze the characteristics and effectiveness of these interventions.
  • To propose evidence-based strategies for clinical application.

Main Methods:

  • A comprehensive literature search was performed across five major databases (CINAHL, Cochrane Library, Embase, PubMed, Web of Science).
  • Included RCTs were published between January 2019 and October 2024.
  • Eight eligible studies were analyzed based on intervention details and outcomes like quality of life, self-management ability, and self-efficacy.

Main Results:

  • Three studies (37.5%) reported significant improvements in quality of life.
  • Three studies (37.5%) showed enhanced self-management ability.
  • Two studies (25.0%) demonstrated increased self-efficacy.
  • Interventions lasting over six months with biweekly or weekly sessions yielded better results.
  • Face-to-face education and telephone support were effective; digital interventions were more successful with interactive features.

Conclusions:

  • A hybrid approach, combining initial face-to-face education with continuous telephone or digital support, appears optimal for adult epilepsy self-management.
  • Intervention duration of six months with regular sessions (biweekly/weekly) is recommended.
  • Interactive components are essential for the effectiveness of digital self-management tools in epilepsy.