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Related Concept Videos

Targeted Muscle Reinnervation: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain03:26

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The protocol outlines the surgical procedure for the treatment of postamputation pain using Targeted Muscle Reinnervation (TMR). TMR will be compared with two other surgical techniques, specifically Regenerative Peripheral Nerve Interface (RPNI) and neuroma excision, followed by immediate burying within muscle under the context of an international, randomized controlled...
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Here, we describe the surgical procedure to perform Regenerative Peripheral Nerve Interface (RPNI) surgery for treating postamputation neuropathic pain in the context of an international, randomized controlled trial (RCT) (ClinicalTrials.gov, NCT05009394). The RCT compares RPNI with two other surgical techniques, namely, Targeted Muscle Reinnervation (TMR) and neuroma excision combined with intra-muscular...
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Related Experiment Video

Updated: Jan 20, 2026

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
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Increased Likelihood of Pregnancy Using an App-Connected Ovulation Test System: A Randomized Controlled Trial.

Sarah Johnson1, Joseph B Stanford2, Graham Warren1

  • 1Clinical Research Department, SPD Development Company Ltd., Bedford, United Kingdom.

Journal of Women'S Health (2002)
|September 5, 2019
PubMed
Summary
This summary is machine-generated.

Fertility tracking apps significantly boost conception rates. Women using an app-connected ovulation test system conceived faster than those not using ovulation testing, increasing pregnancy likelihood within two cycles.

Keywords:
Clearblue Connected Ovulation Test Systemconception ratesluteinizing hormoneovulation testingpregnancy

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Area of Science:

  • Reproductive endocrinology and fertility awareness.

Background:

  • Increasing use of fertility-tracking software applications by women attempting conception.
  • Need to evaluate the efficacy of app-connected ovulation test systems.

Purpose of the Study:

  • To compare conception rates between women using an app-connected ovulation test system and those not using ovulation testing.

Main Methods:

  • Home-based study with 844 volunteers (aged 18-40) seeking conception.
  • Randomized controlled trial: test arm used ovulation test system, control arm did not.
  • Pregnancy rates assessed after one and two cycles.

Main Results:

  • Significantly higher pregnancy rate after one cycle in the test arm (25.4%) vs. control (14.7%; p < 0.001).
  • Continued higher pregnancy rate after two cycles in the test arm (36.2%) vs. control (28.6%; p = 0.026).
  • Test arm had less frequent intercourse but targeted it to the fertile window more effectively.

Conclusions:

  • Utilizing an app-connected ovulation test system to time intercourse within the fertile window enhances conception likelihood.
  • This method increases the probability of conceiving within two menstrual cycles.