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Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
Published on: July 19, 2018
Peritoneal Dialysis in Pediatric Postoperative Cardiac Surgical Patients
Manoj Kumar Sahu1, Bipin C1, Yatin Arora2
1Intensive Care for CTVS, Department of CTVS, CN Centre, All India Institute of Medical Sciences, New Delhi, India.
Insights
Peritoneal dialysis (PD) is a useful renal replacement therapy for pediatric cardiac surgery patients. Factors like serum procalcitonin and potassium levels impact survival, while CPB time and sepsis influence early PD initiation.
Area of Science:
- Pediatric Nephrology
- Cardiac Surgery
- Critical Care Medicine
Background:
- Acute kidney injury (AKI) is a significant complication in pediatric patients following cardiac surgery.
- Peritoneal dialysis (PD) is an established renal replacement therapy (RRT) for AKI.
- Understanding factors influencing PD initiation, duration, and outcomes is crucial for this vulnerable population.
Purpose of the Study:
- To determine the prevalence of AKI requiring PD in pediatric postoperative cardiac surgical patients.
- To identify factors associated with early PD initiation.
- To analyze factors linked to prolonged PD and mortality.
Main Methods:
- Retrospective review of hospital records for 23 pediatric patients (≤12 years) requiring PD post-cardiac surgery.
- Comparison of demographic, intraoperative, and postoperative variables between survivors and non-survivors.
- Analysis of factors associated with short vs. prolonged PD duration and early vs. late PD initiation.
Main Results:
- 3.78% (23/608) of pediatric cardiac surgery patients required PD.
- Non-survivors had higher serum procalcitonin, elevated potassium, and lower urine output compared to survivors.
- Prolonged PD correlated with later PD initiation, higher postoperative creatinine, and mortality. Early PD initiation was linked to CPB time, sepsis, and shorter PD duration.
Conclusions:
- Peritoneal dialysis is a valuable RRT for pediatric patients after cardiac surgery.
- Intraoperative and postoperative variables significantly influence PD initiation timing, duration, and patient survival.
- Further research into optimizing PD management in this cohort is warranted.
Background:
We determined the prevalence of acute kidney injury requiring peritoneal dialysis (PD), the factors associated with early PD initiation, prolonged PD and mortality among pediatric postoperative cardiac surgical patients.
Materials And Methods:
The hospital records of 23 children, aged 12 years or younger, who had undergone cardiac surgery and required PD subsequently, during a 1-year period were reviewed. Demographic data, intraoperative variables, and postoperative complications were compared between survivors and nonsurvivors of PD, between the short and long duration PD groups, and between the early and late PD initiation groups.
Results:
Six hundred and eight pediatric patients who underwent open heart surgery were enrolled in this study. 23 (3.78%) of them required PD. When compared with survivors (n = 11), non survivors (n =12) were more likely to have a higher serum procalcitonin (p = 0.01), higher serum potassium on day 2 (p = 0.001), day 3 (p = 0.04), day of termination of PD (p = 0.001) and a lower urine output on day 3 of PD (p = 0.03). Prolonged PD was associated with time of PD initiation (p = 0.01), a higher postoperative serum creatinine on day 3 (p = 0.01) of PD initiation as well on the day of PD termination (p = 0.01) and the final outcome in terms of survival (p = 0.02). Factors significantly associated with an early PD initiation were CPB time (p = 0.04), sepsis (p = 0.02) and shorter PD duration (p = 0.003).
Conclusion:
PD is very useful mode of renal replacement therapy among pediatric postoperative cardiac surgical patients. The intraoperative and postoperative variables have important association with the time of PD initiation, PD duration and patient survival.
How To Cite This Article:
Sahu MK, Bipin C, Arora Y, Singh SP, Devagouru V, Rajshekar P, et al. Peritoneal Dialysis in Pediatric Postoperative Cardiac Surgical Patients. Indian J Crit Care Med 2019;23(8):371-375.
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