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Quantification of Inflammatory Mediators in Infected Human Tissue-Derived Cells

Quantification of Inflammatory Mediators in Infected Human Tissue-Derived Cells

This video demonstrates the quantification of inflammatory mediators during infection by incubating human lung-tissue-derived immune cells with Haemophilus influenzae. Flow cytometry is used to measure cytokine fluorescence in labeled lymphocytes, correlating with the production of pro-inflammatory cytokines in response to bacterial...

Nanoparticle-Mediated Enhanced Delivery of an Anti-Inflammatory Drug in Microglia-Like Cells

Nanoparticle-Mediated Enhanced Delivery of an Anti-Inflammatory Drug in Microglia-Like Cells

Take cultures of human monocyte-derived microglia-like cells.Introduce nanoparticles containing an anti-inflammatory drug into the experimental culture and the free drug into the control.The nanoparticles feature a hydrophilic shell and a hydrophobic core encapsulating the lipophilic drug.The cells endocytose the nanoparticles, which release the drug intracellularly, enhancing its delivery.The free drug enters by passive diffusion, a process constrained by the concentration gradient, which...

Human In-Vivo Bioassay for the Tissue-Specific Measurement of Nociceptive and Inflammatory Mediators

Human In-Vivo Bioassay for the Tissue-Specific Measurement of Nociceptive and Inflammatory Mediators

A technique is presented for the in-vivo collection of interstitial fluid samples from pertinent tissue sites (here, experimentally inflamed skin) for the measurement of biochemicals mediating pain and...

Obesity

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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...

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This protocol allows a researcher to isolate and characterize tissue-resident macrophages in various hallmark inflamed tissues extracted from diet-induced models of metabolic...

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Obesity care is best delivered after in-depth initial screening and evaluation, using an individualized approach comprising multidisciplinary care, evidence-based lifestyle behavioral change strategies, and frequent follow-up. We illustrate a successful 6 month course of weight loss treatment, resulting in reversal of obesity-related chronic conditions and improvement in diet, sleep, mood, and physical fitness.

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Related Experiment Video

Updated: Jan 20, 2026

Quantification of Inflammatory Mediators in Infected Human Tissue-Derived Cells

Quantification of Inflammatory Mediators in Infected Human Tissue-Derived Cells

Inflammatory Mediators in Obesity

Divya P Kumar¹, Saisudha Koka², Chao Li³

¹Department of Biochemistry, JSS Medical College, CEMR, JSS Academy of Higher Education and Research, Mysore, Karnataka, India.

Mediators of Inflammation

|September 6, 2019

Summary

No abstract available in PubMed .

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Last Updated: Jan 20, 2026

Quantification of Inflammatory Mediators in Infected Human Tissue-Derived Cells

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