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Updated: Jan 20, 2026

The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation
Published on: January 31, 2025
[Pilot experience with indocyanine green navigation in pediatric surgery]
G Guillén1, S López-Fernández1, J A Molino1
1Servicio de Cirugía Pediátrica. Hospital Universitario Vall d'Hebron. Barcelona.
Indocyanine Green (ICG) fluorescence navigation enhances pediatric surgery safety and decision-making. This complication-free technique proved useful in 90% of procedures, particularly in oncology and liver surgery.
Area of Science:
- Surgical Navigation
- Medical Imaging
- Pediatric Surgery
Background:
- Indocyanine Green (ICG) fluorescence is an emerging tool for navigated surgery.
- It offers potential benefits in safety, surgical outcomes, and intraoperative decision-making.
- This pilot series explores ICG navigation in pediatric surgical procedures.
Purpose of the Study:
- To evaluate the utility of ICG fluorescence navigation in various pediatric surgical scenarios.
- To assess its impact on intraoperative decision-making and surgical outcomes.
- To determine the safety and feasibility of ICG navigation in pediatric patients.
Main Methods:
- ICG fluorescence navigation was employed as a decision-making aid in 20 patients (22 procedures) between May 2017 and March 2019.
- Applications included visualization of the biliary tract, vascular/lymphatic structures, neoplastic tissue, and other anatomical landmarks.
- A specialized high-definition system with near-infrared light was utilized.
Main Results:
- The technique was applied in biliary tract procedures (n=6), oncologic procedures (n=9), and miscellaneous cases (n=7).
- No complications were associated with ICG administration.
- ICG navigation provided relevant information or influenced intraoperative decisions in 90% of cases.
Conclusions:
- ICG navigation is a safe and easily performed technique.
- Preliminary findings suggest ICG navigation represents a significant advancement in safety and procedural facilitation for pediatric surgery.
- Its application is particularly promising in pediatric oncology, liver surgery, and neonatal surgery.
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