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Updated: Jan 20, 2026
Murine Orchiectomy and Ovariectomy to Reduce Sex Hormone Production
Published on: November 17, 2023
Infulence of Sex Hormones and Inflammatory Processes on Cognition in Schizophrenia
Krzysztof Krysta1, Marek Krzystanek, Katarzyna Jakuszkowiak-Wojten
1Department of Rehabilitation Psychiatry, Medical University of Silesia, Ziołowa 45/47, 40-635 Katowice, Poland, krysta@mp.pl.
Background:
In the literature we can find evidence that sex hormones are involved the alterations of cognition in schizophrenic patients. Another factor, which may have an impact on cognitive domains in this clinical group inflammatory processes. The objective of this review was to explore studies, in which the role of both immunological factors and sex hormones on cognitive functions in schizophrenia are analyzed.
Methods:
The search of papers covering this topic in PubMed and Google Scholar was performed.
Results:
Endocrine factors like: testosteron, estrogen, as well as immunomodulatory are observed to play a role in cognitive functioning in schizophrenia.
Conclusions:
More studies are necessary to confirm these possible co-relations.
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