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Related Experiment Video

Updated: Jan 20, 2026

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
09:13

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Sensory Integration and Functional Reaching in Children With Rett Syndrome/Rett-Related Disorders.

Wendy Drobnyk1, Karen Rocco1, Sara Davidson1

  • 1Lynch School of Education, Boston College, Chestnut Hill, MA, USA.

Clinical Medicine Insights. Pediatrics
|September 7, 2019
PubMed
Summary
This summary is machine-generated.

Ayres Sensory Integration (ASI) treatment showed a small improvement in hand grasping for children with Rett syndrome. Further research is needed to confirm ASI

Keywords:
Rett syndromehand functionoccupational therapysensory integration

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Area of Science:

  • Neuroscience
  • Occupational Therapy
  • Developmental Pediatrics

Background:

  • Rett syndrome significantly impairs functional hand skills, including reaching and grasping.
  • Stereotypies and sensory processing deficits in Rett syndrome hinder object manipulation.
  • Improved hand function is crucial for participation in daily activities for individuals with Rett syndrome.

Purpose of the Study:

  • To investigate the effects of Ayres Sensory Integration (ASI) treatment on reaching and grasping rates in children with Rett syndrome.
  • To determine if ASI therapy can enhance sensory processing and motor planning for improved hand function.
  • To establish a foundation for developing functional hand use in Rett syndrome.

Main Methods:

  • An interrupted time series design was employed to assess intervention effects.
  • Daily video observations were analyzed over a 7-month period, encompassing baseline, intervention, and post-intervention phases.
  • Changes in reaching and grasping rates were measured as primary outcome variables.

Main Results:

  • A moderate decline in grasping rate was observed during the baseline period.
  • A 15% increase in grasping rate was noted from baseline to the post-intervention period.
  • No significant changes were found in the rate of reaching.

Conclusions:

  • Preliminary findings suggest a modest improvement in hand grasp for children with Rett syndrome following ASI treatment.
  • Larger, diverse studies are necessary to validate the efficacy of ASI for Rett syndrome.
  • The interrupted time series design proved effective for evaluating interventions in rare childhood disorders.