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Higher order aberrations, refractive error development and myopia control: a review.

Rohan Pj Hughes1, Stephen J Vincent1, Scott A Read1

  • 1Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Queensland University of Technology, Brisbane, Australia.

Clinical & Experimental Optometry
|September 7, 2019
PubMed
Summary
This summary is machine-generated.

Higher order aberrations, or optical imperfections, impact eye growth and refractive error. Understanding these aberrations is key to developing effective myopia control strategies.

Keywords:
eye growthhigher order aberrationsmyopia controlrefractive error developmentvisual experience

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Area of Science:

  • Ophthalmology
  • Optometry
  • Vision Science

Background:

  • Ocular growth is influenced by visual experience, with reduced image quality causing predictable changes in eye growth.
  • Higher order aberrations (HOAs) are optical imperfections affecting retinal image quality, even with corrected refractive errors.

Purpose of the Study:

  • To explore the role of higher order aberrations in regulating eye growth and refractive error development.
  • To investigate how HOAs change with age, refractive error, and during visual tasks.
  • To examine HOA changes associated with myopia control interventions.

Main Methods:

  • Review of existing animal and human studies on ocular growth and visual experience.
  • Analysis of the impact of optical defocus and HOAs on retinal image quality.
  • Examination of HOA variations across different age groups and refractive states.
  • Investigation of HOA alterations in response to various myopia control treatments.

Main Results:

  • HOAs reduce retinal image quality and may provide optical signals influencing eye growth and refractive error.
  • HOA characteristics vary significantly with age, refractive error, near work, and accommodation.
  • Distinct HOA changes are observed with myopia control interventions like atropine, multifocal lenses, and orthokeratology.

Conclusions:

  • HOAs are implicated in the mechanisms of axial eye growth, refractive error development, and the efficacy of myopia control.
  • Further research on HOAs in children, during accommodation, and with myopia control treatments is needed to elucidate their role.