Wireless Direct Microampere Current in Wound Healing: Clinical and Immunohistological Data from Two Single Case...

Area of Science:

• Biomedical Engineering
• Wound Healing Research
• Tissue Regeneration

Background:

• Chronic pressure ulcers represent a significant clinical challenge, impacting patient quality of life.
• Existing treatments for non-healing wounds have limitations.
• Electrostimulation (ES) is a recognized modality for wound healing.

Observation:

• Wireless Micro Current Stimulation (WMCS) utilizes air gases to deliver negatively-charged ions to injured tissues.
• WMCS generates comparable tissue potentials to traditional electrode-based ES.
• Two bedridden patients with chronic pressure ulcers were treated with WMCS.

Findings:

• Immunohistochemistry revealed that WMCS suppresses inflammatory responses by reducing granulocyte aggregation.
• WMCS therapy stimulates myofibroblastic activity, crucial for wound contraction.
• The treatment promotes new collagen fiber formation, indicating enhanced tissue repair.

Implications:

• WMCS presents a promising non-invasive, contactless therapeutic option for chronic and non-healing wounds.
• The technology may serve as an adjunct or stand-alone therapy, similar to electrode-based ES.
• WMCS has the potential to be integrated into routine clinical wound management protocols.