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Pediatric posterior fossa incidentalomas.

Danil A Kozyrev1, Shlomi Constantini1, Deki Tsering2

  • 1Department of Pediatric Neurosurgery, Dana Children's Hospital, Tel Aviv Medical Center, Tel Aviv University, 6 Weizmann Street, 64239, Tel Aviv, Israel.

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|September 8, 2019
PubMed
Summary
This summary is machine-generated.

Pediatric posterior fossa incidentalomas can be benign or malignant. Treatment decisions for these incidental brain lesions depend on imaging, symptoms, and tumor type, balancing surgical risks against potential malignancy.

Keywords:
Brain tumorIncidentalomasPediatricPosterior fossa tumor

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Area of Science:

  • Pediatric neuro-oncology
  • Neuroradiology
  • Neurosurgery

Background:

  • Pediatric brain incidentalomas are increasingly diagnosed.
  • The posterior fossa (PF) is a common site for childhood brain tumors, making incidental PF lesions a focus of interest.
  • The natural history of incidental PF lesions in children remains largely unknown.

Purpose of the Study:

  • To investigate the treatment strategies and outcomes for incidental lesions in the pediatric posterior fossa.
  • To characterize the pathology and clinical course of these lesions.
  • To inform management decisions for incidental PF lesions in children.

Main Methods:

  • Retrospective study conducted in two tertiary pediatric centers.
  • Inclusion criteria: incidental PF lesion suspected of being a tumor, diagnosed before age 20.
  • Analysis of treatment strategies, pathology, and outcomes for both operated and non-operated patients.

Main Results:

  • Seventy children (mean age 8.4 years) were included.
  • Pilocytic astrocytomas were the most common pathology (21/39 operated cases).
  • Malignant tumors, including medulloblastomas (5) and ATRT (1), accounted for nearly 10% of cases.

Conclusions:

  • Incidental PF lesions in children encompass both benign and malignant tumors.
  • Management requires careful consideration of radiological appearance, changes over time, location, and symptoms.
  • Treatment decisions involve balancing surgical risks against the potential for high-grade tumors or malignant transformation.