Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment06:47

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

10.1K
We describe here methods for neonatal capsaicin treatment to induce atopic dermatitis in rats and exposure of vaporized formaldehyde to investigate the effects of formaldehyde inhalation on atopic...
10.1K
Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

25.0K
Dermatitis herpetiformis (DH) is a chronic inflammatory condition characterized by an autoimmune reaction between IgA and epidermal transglutaminase (eTG). DH develops in a very small portion of gluten-sensitive and/or celiac patients. The results of this study indicate that DH can also develop in a rhesus monkey host with symptoms of idiopatic...
25.0K
Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis08:25

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

3.5K
Contact hypersensitivity (CHS) is a murine experimental model of allergic contact dermatitis (ACD). CHS is based on sensitization with reactive hapten by painting the shaved skin of the chest and abdomen, with a subsequent ear skin challenge with a diluted hapten, causing a swelling reaction that is assessed in various...
3.5K
The Participant-Reported Implementation Update and Score (PRIUS): A Novel Method for Capturing Implementation-Related Data Over Time06:05

The Participant-Reported Implementation Update and Score (PRIUS): A Novel Method for Capturing Implementation-Related Data Over Time

1.6K
This protocol describes a novel method for collecting and analyzing data related to ongoing implementation called the Participant-Reported Implementation Update and Score (PRIUS). The PRIUS method allows for the efficient and systematic capture of data over time and from multiple viewpoints in healthcare settings.
1.6K
Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)09:38

Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)

833
The Minibioreactor Array (MBRA) is a high-throughput, customizable, continuous-flow culture system that enables the cultivation of complex microbial communities, supporting parallel experiments to study microbiome dynamics, therapeutic interactions, and microbial responses to environmental...
833
A Mouse Ear Model for Allergic Contact Dermatitis Evaluation08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

4.8K
Here, we describe the methods for inducing allergic contact dermatitis in mouse ears by 1-fluoro-2,4-dinitrobenzene (DNFB) and how to evaluate the severity of allergic contact...
4.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

European Society of Contact Dermatitis Guideline for Diagnostic Patch Testing-Recommendations on Best Practice (Update 2026).

Contact dermatitis·2026
Same author

Pathogenesis of cutaneous T-cell lymphoma: Malignant inflammation, immune reprogramming, and microenvironmental drivers.

The Journal of investigative dermatology·2026
Same author

Generalized Pustular Psoriasis in Portugal: Expert Perspectives on Patient Journey, Diagnosis, Therapeutic Goals, and Healthcare Optimization.

Acta medica portuguesa·2026
Same author

Patch Testing in Chronic Hand Eczema: A Multicentre Study in Portugal.

Contact dermatitis·2026
Same author

Bridging the Gap in Chronic Prurigo Care: Evidence-Based Diagnostic and Therapeutic Recommendations from a Delphi Consensus Panel.

Dermatology and therapy·2026
Same author

Patch Test Results With Additions to the European Baseline Series, 2021/22-Joint European Results of the ESSCA<sup>A</sup> and the EBS<sup>B</sup> Working Groups of the ESCD, and the GEIDAC<sup>C</sup>.

Contact dermatitis·2026
Same journal

[Presence of Dermatologists on Social Media: Perception of the Portuguese Population].

Acta medica portuguesa·2026
Same journal

[Sexual Health in Oncology Patients and Cancer Survivors: A Structured Protocol to Address an Unmet Clinical Need at IPO-Porto].

Acta medica portuguesa·2026
Same journal

Hyperthermia in a Teenager: Is it Just a Heat Stroke?

Acta medica portuguesa·2026
Same journal

Cutaneous Polyarteritis Nodosa as the Inaugural Manifestation of Hairy Cell Leukemia.

Acta medica portuguesa·2026
Same journal

Alopecia Neoplastica from Breast Carcinoma: When Hair Loss Hides Something Else.

Acta medica portuguesa·2026
Same journal

[Burnout Among Residents: A Current Perspective].

Acta medica portuguesa·2026
See all related articles

Related Experiment Video

Updated: Jan 19, 2026

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
06:47

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Published on: September 27, 2017

10.1K

Update on Atopic Dermatitis.

Tiago Torres1, Eduarda Osório Ferreira2, Margarida Gonçalo3

  • 1Serviço de Dermatologia. Centro Hospitalar Universitário do Porto. Porto; Instituto de Ciências Biomédicas Abel Salazar. Universidade do Porto. Porto. Portugal.

Acta Medica Portuguesa
|September 8, 2019
PubMed
Summary
This summary is machine-generated.

Atopic dermatitis, a growing global health concern, involves complex genetic and environmental factors impacting skin barrier and immune function. Current treatments aim to control symptoms, but novel therapies are needed for moderate-to-severe cases.

Keywords:
Dermatitis, Atopic/complicationsDermatitis, Atopic/diagnosisDermatitis, Atopic/epidemiologyDermatitis, Atopic/etiologyDermatitis, Atopic/prevention and controlDermatitis, Atopic/therapy

More Related Videos

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

25.0K
Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
08:25

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

Published on: September 26, 2022

3.5K

Related Experiment Videos

Last Updated: Jan 19, 2026

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
06:47

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Published on: September 27, 2017

10.1K
Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

25.0K
Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
08:25

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

Published on: September 26, 2022

3.5K

Area of Science:

  • Dermatology
  • Immunology
  • Genetics

Background:

  • Atopic dermatitis (AD) prevalence has increased globally, becoming a significant health issue.
  • AD is a heterogeneous skin disorder with complex pathogenesis involving genetic and environmental factors.
  • Key factors include skin barrier dysfunction, immune dysregulation, and microbiota dysbiosis.

Purpose of the Study:

  • To provide an overview of atopic dermatitis epidemiology, pathophysiology, clinical features, comorbidities, and current therapies.
  • To summarize diagnostic criteria and disease severity assessment.
  • To highlight therapeutic goals and challenges in managing AD.

Main Methods:

  • A targeted literature search was conducted for this non-systematic review.
  • The review synthesizes information on AD's multifaceted aspects.
  • No specific patient data was analyzed; it's a review of existing knowledge.

Main Results:

  • Diagnosis relies on specific criteria including history and clinical manifestations.
  • Disease severity assessment requires evaluating both objective signs and subjective symptoms.
  • Therapeutic strategies involve basic skin care, trigger avoidance, topical agents, phototherapy, systemic immunosuppressants, and dupilumab.

Conclusions:

  • Managing moderate-to-severe atopic dermatitis remains challenging, necessitating novel treatments.
  • Recent years show improved understanding, but gene-environment interactions require further exploration.
  • Future research should focus on these interactions to enhance pathophysiology understanding, disease severity assessment, and treatment outcomes.