Related Experiment Video
Updated: Jan 19, 2026
Inflammatory Bowel Disease V: Surgical Management
Inflammatory bowel disease in Nigerian children: case series and management challenges
Idowu Senbanjo1,2, Ayodeji Akinola2, Tolulope Kumolu-Johnson2
1Department of Paediatrics and Child Health, Lagos State University College of Medicine , Ikeja, Lagos, Nigeria.
Insights
Inflammatory bowel disease (IBD) is uncommon in sub-Saharan Africa, but five Nigerian pediatric cases reveal diagnostic and management challenges. Early consideration of IBD is crucial for children with persistent gastrointestinal symptoms.
Area of Science:
- Pediatric Gastroenterology
- Tropical Medicine
- Inflammatory Bowel Disease (IBD)
Background:
- Inflammatory bowel disease (IBD) is infrequently diagnosed in sub-Saharan Africa.
- This study focuses on five pediatric cases from Nigeria to understand IBD's presentation and challenges in this region.
Purpose of the Study:
- To highlight the occurrence and clinical presentation patterns of IBD in Nigerian children.
- To identify management challenges associated with pediatric IBD in sub-Saharan Africa.
Main Methods:
- Retrospective review of diagnosed IBD cases between January 2011 and December 2018.
- Cases were identified at the Lagos State University Teaching Hospital's Paediatric Gastroenterology, Hepatology and Nutrition Unit.
Main Results:
- Five pediatric cases of IBD were analyzed, with a median age of 9 years (range 7-13).
- Three cases presented with persistent bloody diarrhea, initially misdiagnosed.
- Two cases were diagnosed post-surgically for acute abdominal conditions.
Conclusions:
- IBD should be considered in the differential diagnosis for Nigerian children presenting with chronic bloody diarrhea, weight loss, or abdominal pain.
- Increased awareness and diagnostic vigilance are necessary for pediatric IBD in tropical regions.
Abstract:
Inflammatory bowel disease (IBD) is rare in sub-Saharan Africa. Five cases in Nigerian children are presented to highlight the occurrence, pattern of clinical presentation and management challenges. The patients were identified following a retrospective review of all diagnosed cases of IBD between 1 January 2011 and 31 December 2018 seen at the Paediatric Gastroenterology, Hepatology and Nutrition Unit of Lagos State University Teaching Hospital. The median age (range) was 9 (7-13) years. Three cases were diagnosed because bloody diarrhoea persisted despite treatment at various health facilities for its common causes in the tropics and sub-tropics. The other two cases were confirmed after surgical intervention undertaken for symptoms of acute abdomen owing to appendicitis and intestinal obstruction. IBD should be considered in the differential diagnosis of children with chronic symptoms of bloody diarrhoea, weight loss, abdominal pain or abdominal masses.
Related Concept Videos
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease IV: Pharmacological Management
Pharmacologic...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
09:04DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
