Related Experiment Video

Updated: Jan 19, 2026

Inflammatory Bowel Disease V: Surgical Management
01:21

Inflammatory Bowel Disease V: Surgical Management

458

Inflammatory bowel disease in Nigerian children: case series and management challenges

Idowu Senbanjo1,2, Ayodeji Akinola2, Tolulope Kumolu-Johnson2

  • 1Department of Paediatrics and Child Health, Lagos State University College of Medicine , Ikeja, Lagos, Nigeria.

Insights

Inflammatory bowel disease (IBD) is uncommon in sub-Saharan Africa, but five Nigerian pediatric cases reveal diagnostic and management challenges. Early consideration of IBD is crucial for children with persistent gastrointestinal symptoms.

Area of Science:

  • Pediatric Gastroenterology
  • Tropical Medicine
  • Inflammatory Bowel Disease (IBD)

Background:

  • Inflammatory bowel disease (IBD) is infrequently diagnosed in sub-Saharan Africa.
  • This study focuses on five pediatric cases from Nigeria to understand IBD's presentation and challenges in this region.

Purpose of the Study:

  • To highlight the occurrence and clinical presentation patterns of IBD in Nigerian children.
  • To identify management challenges associated with pediatric IBD in sub-Saharan Africa.

Main Methods:

  • Retrospective review of diagnosed IBD cases between January 2011 and December 2018.
  • Cases were identified at the Lagos State University Teaching Hospital's Paediatric Gastroenterology, Hepatology and Nutrition Unit.

Main Results:

  • Five pediatric cases of IBD were analyzed, with a median age of 9 years (range 7-13).
  • Three cases presented with persistent bloody diarrhea, initially misdiagnosed.
  • Two cases were diagnosed post-surgically for acute abdominal conditions.

Conclusions:

  • IBD should be considered in the differential diagnosis for Nigerian children presenting with chronic bloody diarrhea, weight loss, or abdominal pain.
  • Increased awareness and diagnostic vigilance are necessary for pediatric IBD in tropical regions.

Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
458
Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
532
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
971
DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat09:04

DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat

DNBS/TNBS induced colitis offers an alternative and inexpensive method to study the pathobiology of inflammatory bowel disease. The protocol discussed in this paper outlines the successful application of DNBS to induce colitis in mice and rats and allows one to thoroughly study host-mediated intestinal...
48.6K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
645
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
908