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A Novel Approach to Monitoring Graft Neovascularization in the Human Gingiva
Published on: January 12, 2019
Smart Graft Monitoring After the Fontan Operation
John F Rhodes1, Madalsa Patel2, Redmond P Burke3
1The Medical University of South Carolina, Charleston, SC, USA.
Insights
Monitoring children after the Fontan operation is crucial. Suturing a CardioMEMS sensor during surgery allows noninvasive Fontan pressure measurements in daily life.
Area of Science:
- Pediatric Cardiology
- Biomedical Engineering
- Surgical Innovation
Background:
- The Fontan operation creates a unique physiology with elevated venous pressure and low cardiac output in children with congenital heart disease.
- Current monitoring requires invasive cardiac catheterization in a specialized lab setting, limiting real-world data.
- Accurate, noninvasive pressure monitoring is needed for optimal Fontan patient management.
Observation:
- The CardioMEMS sensor, typically used for heart failure management, was sutured into the Fontan conduit during the operation.
- This placement aimed to enable direct measurement of Fontan pathway pressures.
- The goal was to assess the feasibility of noninvasive pressure retrieval.
Findings:
- The study hypothesizes that the implanted CardioMEMS sensor can accurately measure Fontan pressures noninvasively.
- This method would provide continuous, real-world hemodynamic data outside the catheterization lab.
- Successful implantation and data retrieval are anticipated.
Implications:
- This innovation could revolutionize Fontan patient follow-up, enabling proactive management.
- Noninvasive monitoring may lead to earlier detection of complications and improved long-term outcomes.
- It offers a less burdensome and more comprehensive approach to assessing Fontan physiology.
Abstract:
The Fontan operation for children with congenital heart disease places them in a physiological state of mildly elevated systemic venous pressure and low-normal cardiac output. Consequently, close follow-up is imperative, yet currently no method is available to obtain Fontan pressures without direct measurements in the cardiac catheterization laboratory while supine and sedated. We hypothesize that by suturing the CardioMEMS sensor device into the Fontan conduit during the standard Fontan operation for a child with single ventricular physiology, clinicians can accurately retrieve Fontan pathway pressure measurements noninvasively during normal physiological states.
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