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Updated: Jan 19, 2026

A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position
Published on: April 1, 2022
Ross Procedure: How to Do It and How to Teach It
Jeremy L Herrmann1,2, Amanda R Stram1, John W Brown1,2
1Division of Thoracic and Cardiovascular Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Insights
The Ross procedure offers a solution for aortic valve replacement (AVR) in patients with bicuspid aortic valves, avoiding lifelong anticoagulation. This technique uses the patient's own pulmonary valve for aortic valve replacement.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Pediatric Cardiac Surgery
Background:
- Aortic valve replacement (AVR) in children faces challenges with small prosthesis sizes, lack of growth, and anticoagulation risks.
- The Ross procedure, utilizing a pulmonary valve autograft, presents advantages for pediatric and adult AVR.
- Standard AVR prostheses may not be suitable for all pediatric patients due to size and growth limitations.
Purpose of the Study:
- To describe the surgical technique for the Ross procedure including ascending aorta replacement.
- To present a case of Ross AVR in an adult with a bicuspid aortic valve, stenosis, insufficiency, and aortic dilation.
- To highlight the benefits of the Ross procedure in specific patient populations.
Main Methods:
- Detailed description of the current Ross AVR technique, incorporating ascending aorta replacement with a prosthetic graft.
- Video documentation of the procedure performed on an adult male patient.
- Surgical management of a bicuspid aortic valve with mixed stenosis and insufficiency and a dilated ascending aorta.
Main Results:
- The Ross procedure was successfully performed, addressing aortic valve pathology and aortic dilation.
- The technique allows for the use of a living autograft, potentially accommodating growth and reducing long-term complications.
- Avoidance of mechanical prosthetic valves eliminates the need for long-term anticoagulation.
Conclusions:
- The Ross procedure is a viable and advantageous option for aortic valve replacement, particularly in younger patients and those with specific aortic pathologies.
- This technique effectively manages complex aortic valve disease and ascending aorta issues.
- The use of a pulmonary autograft in the Ross procedure offers a biological solution to AVR challenges.
Abstract:
Prosthesis choice for aortic valve replacement (AVR) in children is frequently compromised by unavailability of prostheses in very small sizes, the lack of prosthetic valve growth, and risks associated with long-term anticoagulation. The Ross procedure with pulmonary valve autograft offers several advantages for pediatric and adult patients. We describe our current Ross AVR technique including replacement of the ascending aorta with a prosthetic graft. The procedure shown in the video involves an adult-sized male with a bicuspid aortic valve, mixed aortic stenosis and insufficiency, and a dilated ascending aorta.
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