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Updated: Jan 19, 2026

A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position
Published on: April 1, 2022
Ross Procedure: How to Do It and How to Teach It
Jeremy L Herrmann1,2, Amanda R Stram1, John W Brown1,2
1Division of Thoracic and Cardiovascular Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
The Ross procedure offers a solution for aortic valve replacement (AVR) in patients with bicuspid aortic valves, avoiding lifelong anticoagulation. This technique uses the patient's own pulmonary valve for aortic valve replacement.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Pediatric Cardiac Surgery
Background:
- Aortic valve replacement (AVR) in children faces challenges with small prosthesis sizes, lack of growth, and anticoagulation risks.
- The Ross procedure, utilizing a pulmonary valve autograft, presents advantages for pediatric and adult AVR.
- Standard AVR prostheses may not be suitable for all pediatric patients due to size and growth limitations.
Purpose of the Study:
- To describe the surgical technique for the Ross procedure including ascending aorta replacement.
- To present a case of Ross AVR in an adult with a bicuspid aortic valve, stenosis, insufficiency, and aortic dilation.
- To highlight the benefits of the Ross procedure in specific patient populations.
Main Methods:
- Detailed description of the current Ross AVR technique, incorporating ascending aorta replacement with a prosthetic graft.
- Video documentation of the procedure performed on an adult male patient.
- Surgical management of a bicuspid aortic valve with mixed stenosis and insufficiency and a dilated ascending aorta.
Main Results:
- The Ross procedure was successfully performed, addressing aortic valve pathology and aortic dilation.
- The technique allows for the use of a living autograft, potentially accommodating growth and reducing long-term complications.
- Avoidance of mechanical prosthetic valves eliminates the need for long-term anticoagulation.
Conclusions:
- The Ross procedure is a viable and advantageous option for aortic valve replacement, particularly in younger patients and those with specific aortic pathologies.
- This technique effectively manages complex aortic valve disease and ascending aorta issues.
- The use of a pulmonary autograft in the Ross procedure offers a biological solution to AVR challenges.
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