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Related Experiment Video

Updated: Jan 19, 2026

Long-patch Base Excision Repair
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Modified Single-Patch versus Two-Patch Repair for Atrioventricular Septal Defect: A Systematic Review and

Rohit S Loomba1, Saul Flores2, Enrique G Villarreal2

  • 1Cardiology, Pediatrics, Advocate Children's Hospital, Oak Lawn, IL, USA.

World Journal for Pediatric & Congenital Heart Surgery
|September 10, 2019
PubMed
Summary
This summary is machine-generated.

The modified single-patch repair for atrioventricular septal defects reduces cardiopulmonary bypass and cross-clamp times. However, this technique did not show significant improvements in other critical postoperative outcomes compared to the two-patch repair.

Keywords:
atrioventricular septal defectcardiac surgical proceduresoutcome assessmentpediatrics

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Area of Science:

  • Cardiology
  • Pediatric Surgery
  • Medical Technology

Background:

  • Atrioventricular septal defects (ASDs) are congenital heart conditions requiring surgical repair.
  • The choice of surgical technique, specifically single-patch versus two-patch repair, is a subject of ongoing clinical evaluation.
  • Postoperative outcomes following ASD repair are critical for patient recovery and long-term health.

Purpose of the Study:

  • To conduct a meta-analysis comparing the modified single-patch repair technique with the traditional two-patch repair for ASDs.
  • To evaluate the impact of the modified single-patch technique on various postoperative outcomes.

Main Methods:

  • A systematic review identified studies comparing modified single-patch and two-patch ASD repair techniques.
  • Meta-analysis using fixed-effects and random-effects models was performed based on heterogeneity.
  • Meta-regression was employed to assess the influence of other factors on outcomes.

Main Results:

  • Ten studies involving 724 patients were included in the meta-analysis.
  • The modified single-patch repair was associated with significantly reduced cardiopulmonary bypass time (mean difference -28.53 minutes) and cross-clamp time (mean difference -22.69 minutes).
  • No significant differences were observed in mechanical ventilation duration, ICU/hospital length of stay, reoperation rates, or mortality between the two techniques.

Conclusions:

  • The modified single-patch repair technique for atrioventricular septal defects offers a significant advantage by reducing cardiopulmonary bypass and cross-clamp times.
  • Despite the reduction in procedural times, the modified single-patch repair did not demonstrate statistically significant improvements in other key postoperative outcomes when compared to the two-patch repair.