Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

7.3K
This training protocol uses computerized training to teach technology-related everyday functional skills. These skills include financial skills, travel and transit, as well as medication...
7.3K
Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats11:01

Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats

10.2K
The goal of the protocol presented here is to describe procedures to expose rats to moderate levels of alcohol during prenatal brain development and to quantify resulting alterations in social behavior during adulthood.
10.2K
Comparing the Frequency Effect Between the Lexical Decision and Naming Tasks in Chinese08:08

Comparing the Frequency Effect Between the Lexical Decision and Naming Tasks in Chinese

9.7K
Researchers adopt both the lexical decision task and the naming task to investigate some important topics such as character/word recognition by comparing the frequency effect between these two tasks. This article introduces this approach through two exemplar experiments and elaborates on the underlying...
9.7K
A Networked Desktop Virtual Reality Setup for Decision Science and Navigation Experiments with Multiple Participants06:28

A Networked Desktop Virtual Reality Setup for Decision Science and Navigation Experiments with Multiple Participants

6.3K
This paper describes a method for conducting multi-user experiments on decision-making and navigation using a networked computer...
6.3K
Echocardiography-guided Injection for Targeted and Reliable Intramyocardial Stem Cell Delivery in a Rat Model of Myocardial Infarction06:47

Echocardiography-guided Injection for Targeted and Reliable Intramyocardial Stem Cell Delivery in a Rat Model of Myocardial Infarction

504
This article details an optimized protocol for echocardiography-guided intramyocardial injections in rat models of myocardial infarction using a 29 G x 88 mm needle. This technique ensures robust, precise, and reproducible delivery of therapeutic agents directly into the peri-infarct zone.
504
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

39.4K
Psoriasis is a chronic, immune-mediated inflammatory skin disease. The Goeckerman regimen, formulated for the treatment of psoriasis, consists of exposure to ultraviolet B (UVB) light and application of crude coal tar (CCT). The following protocol is for the administration of Goeckerman therapy for the treatment of moderate-to-severe...
39.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Impact of Sparse Datasets When Harmonizing Data from Studies with Different Measures of the Same Construct.

Prevention science : the official journal of the Society for Prevention Research·2024
Same author

Correction: Re-envisioning, Retooling, and Rebuilding Prevention Science Methods to Address Structural and Systemic Racism and Promote Health Equity.

Prevention science : the official journal of the Society for Prevention Research·2024
Same author

Retrospective Psychometrics and Effect Heterogeneity in Integrated Data Analysis: Commentary on the Special Issue.

Prevention science : the official journal of the Society for Prevention Research·2023
Same author

Re-envisioning, Retooling, and Rebuilding Prevention Science Methods to Address Structural and Systemic Racism and Promote Health Equity.

Prevention science : the official journal of the Society for Prevention Research·2022
Same author

The impact of social rhythm and sleep disruptions on waist circumference after job loss: A prospective 18-month study.

Obesity (Silver Spring, Md.)·2022
Same author

Secondary Analysis to Inform the Development of Adaptive Preventive Interventions.

Clinical child and family psychology review·2022
Same journal

Mothers' and fathers' social support trajectories and children's prosocial development: A dyadic perspective.

Development and psychopathology·2026
Same journal

Developmental trajectories of child maltreatment: Associations with internalizing and externalizing symptoms.

Development and psychopathology·2026
Same journal

Trajectories of distressing psychotic-like experience in youth: the interplay of recent negative life events and screen time.

Development and psychopathology·2026
Same journal

Bidirectional associations between maternal and paternal depressive symptoms across the postpartum period: Contributions of maternal prenatal depression and childhood neglect.

Development and psychopathology·2026
Same journal

Psychological resilience moderates the relationship between childhood adversity, brain network connectivity, and wellness.

Development and psychopathology·2026
Same journal

The long view: Lie-telling trajectories, ages 6 to 19 years.

Development and psychopathology·2026
See all related articles

Related Experiment Video

Updated: Jan 19, 2026

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

7.3K

Using baseline target moderation to guide decisions on adapting prevention programs.

George W Howe1

  • 1Department of Psychology, George Washington University, Washington, DC, USA.

Development and Psychopathology
|September 10, 2019
PubMed
Summary
This summary is machine-generated.

Prevention science can be improved by assessing baseline target moderated mediation (BTMM). This method evaluates how intervention effects change based on initial target levels, aiding tailored family support.

Keywords:
adaptationpreventionprogram moderated mediation

More Related Videos

Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats
11:01

Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats

Published on: December 14, 2014

10.2K
Comparing the Frequency Effect Between the Lexical Decision and Naming Tasks in Chinese
08:08

Comparing the Frequency Effect Between the Lexical Decision and Naming Tasks in Chinese

Published on: April 1, 2016

9.7K

Related Experiment Videos

Last Updated: Jan 19, 2026

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

7.3K
Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats
11:01

Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats

Published on: December 14, 2014

10.2K
Comparing the Frequency Effect Between the Lexical Decision and Naming Tasks in Chinese
08:08

Comparing the Frequency Effect Between the Lexical Decision and Naming Tasks in Chinese

Published on: April 1, 2016

9.7K

Area of Science:

  • Prevention Science
  • Developmental Psychology
  • Behavioral Health

Background:

  • Adapting interventions to individual family needs is crucial in prevention science.
  • Early recognition of personalized intervention needs by pioneers like Tom Dishion.
  • Need for methods to assess how intervention effects vary by baseline characteristics.

Purpose of the Study:

  • Introduce and define baseline target moderated mediation (BTMM) for prevention trials.
  • Illustrate four forms of BTMM: compensatory, rich-get-richer, crossover, and differential iatrogenic effects.
  • Provide a strategy for evaluating meaningful preventive effects using thresholds and mechanisms.

Main Methods:

  • Utilizing prevention trials to assess BTMM.
  • Analyzing intervention effects mediated by changes in specific targets.
  • Employing simulated data to model BTMM curves and subgroup identification.

Main Results:

  • Demonstrated four distinct forms of BTMM in recent trials.
  • Presented a strategy for evaluating preventive effects based on thresholds.
  • Illustrated how baseline levels influence intervention risk reduction and potential iatrogenic effects.

Conclusions:

  • BTMM offers a framework for understanding personalized intervention effects.
  • Identifying subgroups benefiting from or harmed by interventions is possible.
  • Results inform program adaptation for enhanced effectiveness and safety.