Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Catalysis02:50

Catalysis

30.1K
The presence of a catalyst affects the rate of a chemical reaction. A catalyst is a substance that can increase the reaction rate without being consumed during the process. A basic comprehension of a catalysts’ role during chemical reactions can be understood from the concept of reaction mechanisms and energy diagrams.
30.1K
Fabrication of a Solution-gated Indium-Tin-Oxide-based One-piece Transistor Enabling Sensitive Biosensing10:45

Fabrication of a Solution-gated Indium-Tin-Oxide-based One-piece Transistor Enabling Sensitive Biosensing

669
This protocol describes the fabrication of a one-piece indium-tin-oxide (ITO)-based ion-sensitive field-effect transistor (ISFET), which can be constructed as a solution-gated FET sensor (e.g., pH sensor) using a short and simple process (approximately half a day). This one-piece ITO-ISFET can also be applied to...
669
Sigma's Non-specific Protease Activity Assay - Casein as a Substrate11:37

Sigma's Non-specific Protease Activity Assay - Casein as a Substrate

78.3K
Proteases break peptide bonds. In the lab, it is often necessary to measure and/or compare the activity of proteases. Sigma's non-specific protease activity assay may be used as a standardized procedure to determine the activity of...
78.3K
Non-gated Ion Channels01:24

Non-gated Ion Channels

8.0K
Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
Compared to the gated ion channels, the non-gated channels, also known as leakage or passive channels, have no gating mechanism....
8.0K
Mechanically-gated Ion Channels01:12

Mechanically-gated Ion Channels

7.6K
Mechanically-gated ion channels are proteins found in eukaryotic and prokaryotic cell membranes that open in response to mechanical stress. Tension, compression, swelling, and shear stress can alter the conformation of the protein, opening a transmembrane channel that allows the passage of ions for signal transmission. In eukaryotes, mechanically-gated channels are distributed in several regions like the neurons, lungs, skin, bladder, and heart, where they play critical roles in numerous...
7.6K
Ligand-Gated Ion Channel Receptor: Gating Mechanism01:30

Ligand-Gated Ion Channel Receptor: Gating Mechanism

3.8K
Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...
3.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lattice-Electron Synergistic Pinning Strategy for Intensified Regeneration of Spent Ternary Cathodes.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Defect-Engineered Scaling of Lead-Free Ferroelectrics with Ultra-Low-Voltage Switching.

Nano letters·2026
Same author

Redox Staining of Metallic Lithium inside Batteries for Multimodal Visualization and Identification with Multiscale Spatial Resolution.

Journal of the American Chemical Society·2026
Same author

Using a functional near-infrared spectroscopy-guided brain-computer interface to facilitate observational imitation after stroke.

Annals of physical and rehabilitation medicine·2026
Same author

VEXAS syndrome with atypical presentation: A case report and review of eosinophils in cutaneous biopsies.

JAAD case reports·2026
Same author

SEI Characterization Using XPS: Resolving Rinsing Effects through Cryogenic Implementation.

ACS applied materials & interfaces·2026

Related Experiment Video

Updated: Jan 19, 2026

Fabrication of a Solution-gated Indium-Tin-Oxide-based One-piece Transistor Enabling Sensitive Biosensing
10:45

Fabrication of a Solution-gated Indium-Tin-Oxide-based One-piece Transistor Enabling Sensitive Biosensing

Published on: August 29, 2025

669

A Two-Dimensional MoS2 Catalysis Transistor by Solid-State Ion Gating Manipulation and Adjustment (SIGMA).

Yecun Wu1, Stefan Ringe2,3, Chun-Lan Wu4

  • 1Department of Electrical Engineering , Stanford University , Stanford , California 94305 , United States.

Nano Letters
|September 10, 2019
PubMed
Summary

Researchers developed a new Solid-State Ion Gating Manipulation and Adjustment (SIGMA) method to dynamically control catalyst activity. This technique tunes catalytic performance in real-time, offering unprecedented control over chemical reactions.

Keywords:
Catalysis transistorelectrocatalysissolid-state ion gatingtwo-dimensional materials

More Related Videos

Catalysis: Homogenious and Heterogeneous Catalysis
02:50

Catalysis: Homogenious and Heterogeneous Catalysis

30.1K
Sigma's Non-specific Protease Activity Assay - Casein as a Substrate
11:37

Sigma's Non-specific Protease Activity Assay - Casein as a Substrate

Published on: September 17, 2008

78.3K

Related Experiment Videos

Last Updated: Jan 19, 2026

Fabrication of a Solution-gated Indium-Tin-Oxide-based One-piece Transistor Enabling Sensitive Biosensing
10:45

Fabrication of a Solution-gated Indium-Tin-Oxide-based One-piece Transistor Enabling Sensitive Biosensing

Published on: August 29, 2025

669
Catalysis: Homogenious and Heterogeneous Catalysis
02:50

Catalysis: Homogenious and Heterogeneous Catalysis

30.1K
Sigma's Non-specific Protease Activity Assay - Casein as a Substrate
11:37

Sigma's Non-specific Protease Activity Assay - Casein as a Substrate

Published on: September 17, 2008

78.3K

Area of Science:

  • Materials Science
  • Electrochemistry
  • Catalysis

Background:

  • Catalyst activity is typically enhanced by tuning composition, structure, defects, or strain.
  • Existing methods lack dynamic control during catalytic reactions.
  • Electrochemical intercalation is one method to tune catalyst properties.

Purpose of the Study:

  • To introduce a novel method for dynamic catalyst activity control.
  • To demonstrate real-time, reversible tuning of catalytic performance.
  • To investigate the mechanism of solid-state ion gating manipulation and adjustment (SIGMA).

Main Methods:

  • Utilized a catalysis transistor incorporating SIGMA.
  • Employed electrostatic doping to achieve high electron concentrations (> 5 × 10^13 cm^-2) on catalyst surfaces.
  • Investigated the hydrogen evolution reaction (HER) on MoS2 using theoretical and experimental approaches.

Main Results:

  • SIGMA enabled in situ, continuous, dynamic, and reversible tuning of catalytic activity.
  • Overpotential at 10 mA/cm^2 was tuned by over 100 mV.
  • Tafel slope was dynamically adjusted by approximately 100 mV/dec.
  • Modulated chemical potential of reaction intermediates and electrical conductivity.

Conclusions:

  • SIGMA provides a new paradigm for controlling catalyst activity.
  • This method offers dynamic and reversible tuning of catalytic reactions.
  • Demonstrated effectiveness on MoS2 for hydrogen evolution reaction.