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Rapid Identification of Gram Negative Bacteria from Blood Culture Broth Using MALDI-TOF Mass Spectrometry
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Characteristics, Associated Diseases, and Management of Gram-negative Toe-web Infection: A French Experience

Anne Goiset1, Brigitte Milpied, Aurélie Marti

  • 1Department of Dermatology, Bordeaux University Hospital, 33000 Bordeaux, France.

Acta Dermato-Venereologica
|September 11, 2019
PubMed

Insights

Gram-negative toe-web infections often recur. Managing underlying conditions like eczema and psoriasis significantly reduces relapse rates, highlighting the importance of comprehensive treatment strategies.

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Microbiology

Background:

  • Gram-negative toe-web infections present challenges including pain, delayed healing, and recurrence.
  • Pseudomonas aeruginosa is a common pathogen in these infections.
  • Predisposing factors significantly influence infection chronicity and relapse.

Purpose of the Study:

  • To detail clinical features and management of Gram-negative toe-web infections.
  • To identify predisposing factors and associated diseases.
  • To assess the impact of managing associated conditions on infection recurrence.

Main Methods:

  • Retrospective real-life study design.
  • Inclusion of 62 patients diagnosed with Gram-negative toe-web infection.
  • Analysis of clinical data, bacterial isolates, predisposing factors, and treatment outcomes.

Main Results:

  • Eczema (66%), Tinea pedis (58%), humidity (42%), and vascular disorders (40%) were common predisposing factors.
  • 31 out of 62 patients experienced recurrent infections.
  • Successful management of associated diseases like eczema and psoriasis correlated with non-recurrence.

Conclusions:

  • Standardized management protocols for Gram-negative toe-web infections are recommended.
  • Effective diagnosis and treatment of associated conditions are crucial for preventing relapse.
  • Controlling underlying dermatological and vascular issues improves patient outcomes.
Keywords:
Pseudomonas aeruginosacontact dermatitiseczemaGram-negative toe-web infection

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