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Updated: Jan 19, 2026
Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Congenital Lymphatic Malformation and Aortic Aneurysm in a Patient with TSC2 Mutation
Adelheid Wiemer-Kruel1, Hans Mayer1, Peter Ewert2
1Clinic for Children and Adolescents, Epilepsy Center Kork, Tuberous Sclerosis Center, Kehl-Kork, Germany.
Abstract:
We present a 7-year-old boy with tuberous sclerosis and congenital segmental lymphedema (CSL) of the left leg, as well as two aortic aneurysms. He was treated with everolimus (EVE) since the age of 14 months. His CSL regressed under treatment with EVE. His first aneurysms required operative intervention at age of 17 months. Four months afterward a new aortic aneurysm had been detected above the Dracon graft, but this one remained stable since that time. The patient didn't experience severe side effects. EVE has been well tolerated without disturbance of somatic growth or serious adverse effect.
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1Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana
2Mechanical Engineering & Materials Science, Washington University in St. Louis, St Louis, Missouri
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