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Updated: Jan 19, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Systemic and Autoimmune Diseases.

Xavier Delgadillo1, Adrián E Ortega2, Alejandro Moreira Greco3

  • 1Centre Médico Chirurgical Volta, La Chaux-de-Fonds, Switzerland.

Clinics in Colon and Rectal Surgery
|September 12, 2019
PubMed
Summary
This summary is machine-generated.

This review covers how systemic and autoimmune diseases manifest in the perianal area and skin. Understanding these clinical features is crucial for accurate diagnosis and management of related integumentary conditions.

Keywords:
acanthosis nigricansglucagonoma syndromeleukemic infiltrationpemphigus vulgarispsoriasispyoderma gangrenosumvitiligo

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Area of Science:

  • Dermatology
  • Rheumatology
  • Gastroenterology

Background:

  • The perianal region and surrounding skin can be affected by various systemic and autoimmune conditions.
  • Early recognition of integumentary manifestations is vital for patient outcomes.

Purpose of the Study:

  • To review the clinical features of systemic and autoimmune diseases impacting the perianal area.
  • To highlight the importance of dermatological assessment in diagnosing systemic illnesses.

Main Methods:

  • Literature review of clinical presentations.
  • Analysis of case studies and relevant research.

Main Results:

  • Detailed description of characteristic skin lesions and symptoms in the perianal region.
  • Correlation of specific integumentary findings with underlying systemic diseases.

Conclusions:

  • Systemic and autoimmune diseases often present with distinct perianal and integumentary signs.
  • Integrated diagnostic approaches are essential for effective patient care.