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Updated: Jan 19, 2026
Negative and Cognitive Symptoms of Schizophrenia
Persistent negative symptoms in schizophrenia: survey of Canadian psychiatrists
Danyael Lutgens1, Martin Lepage2, Rahul Manchanda3
1PhD Candidate, McGill University Department of Psychiatry; Prevention and Early Intervention Program for the Psychoses, Douglas Mental Health University Institute, Montreal, Quebec, Canada.
Abstract:
A sample of 206 Canadian psychiatrists who routinely treat patients with psychotic disorders were randomly surveyed regarding their knowledge and practice in relation to persistent negative symptoms of schizophrenia. Large majorities reported observing a high prevalence of persistent negative symptoms that do not respond to available treatments (83%), have a profound impact on functional outcomes (96.5%) and contribute to family burden. Almost half the sample (43%) recognised the importance of formally assessing persistent symptoms and nearly a third (30%) indicated that this was a part of their usual practice. These survey results correspond with recent consensus and highlight the importance and challenge of treating persistent negative symptoms in schizophrenia.
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