Related Experiment Video
Updated: Jan 19, 2026

Classical Short-Delay Eyeblink Conditioning in One-Year-Old Children
Published on: September 1, 2018
Classical versus controlled rapid sequence induction and intubation in children with bleeding tonsils (a
Melanie E Kemper1,2, Philipp K Buehler1, Achim Schmitz1
1Department of Anaesthesia, University Children's Hospital, Zurich, Switzerland.
Gentle bag-mask ventilation during anesthesia for post-tonsillectomy bleeding in children improved oxygen levels and laryngoscopy views. This controlled rapid sequence induction and intubation (RSII) technique reduced hypoxemia and hypertension without increasing complications.
Area of Science:
- Pediatric Anesthesiology
- Airway Management
- Surgical Complications
Background:
- Post-tonsillectomy bleeding is a common pediatric surgical emergency requiring prompt airway management.
- Rapid sequence induction and intubation (RSII) is critical, but hypoxemia and difficult laryngoscopy are significant risks.
- The role of bag-mask ventilation during RSII in this specific context remains debated.
Purpose of the Study:
- To evaluate if bag-mask ventilation during RSII for post-tonsillectomy bleeding in children reduces hypoxemia and difficult laryngoscopy.
- To assess if this technique increases perioperative respiratory complications.
- To compare controlled RSII (with bag-mask ventilation) versus classical RSII (apneic technique).
Main Methods:
- Retrospective analysis of medical records and anesthesia data from 2005-2017 for children undergoing revision surgery for tonsil bleeding.
- Categorization of RSII into classical (apneic) or controlled (bag-mask ventilation).
- Primary outcomes included incidence of hypoxemia, laryngoscopy view grade, and intubation difficulty; secondary outcomes were hemodynamic changes and adverse events.
Main Results:
- Controlled RSII was used in 81 children (88 revisions) and classical RSII in 22 children (22 revisions).
- Controlled RSII was associated with significantly less severe hypoxemia (P=.025) and improved laryngoscopy views (P=.048).
- Hypertension was less frequent with controlled RSII (P<.001), with no increase in tracheal intubation difficulties or perioperative pulmonary morbidity.
Conclusions:
- Controlled RSII with bag-mask ventilation offers advantages over classical RSII in children with post-tonsillectomy bleeding.
- This technique may be a strategic option to mitigate hypoxemia, difficult laryngoscopy, and hypertension during anesthesia induction.
- Bag-mask ventilation in this setting did not correlate with increased pulmonary morbidity.
Related Concept Videos
07:36Classical Short-Delay Eyeblink Conditioning in One-Year-Old Children
04:46A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation
11:19Guidelines for Elective Pediatric Fiberoptic Intubation
08:53Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma
07:14A Method to Study Adaptation to Left-Right Reversed Audition
08:46An Improved Method for Rapid Intubation of the Trachea in Mice

