[Hypertension management in chronic kidney diseases : an unachieved symphony]

Area of Science:

• Nephrology
• Cardiology
• Internal Medicine

Background:

• Arterial hypertension (HT) is prevalent in patients with chronic kidney disease (CKD), acting as both a cause and consequence.
• HT significantly worsens prognosis in CKD patients, leading to high cardiovascular morbidity and mortality.
• Current guidelines for managing HT in CKD patients are often ambiguous for general practitioners.

Purpose of the Study:

• To highlight the critical need for systematic screening and optimal management of HT in CKD.
• To discuss the diagnostic approaches and therapeutic targets for HT in the context of kidney disease.
• To review the pathophysiological mechanisms linking HT and CKD.

Main Methods:

• Literature review of recent studies on HT and CKD.
• Analysis of pathophysiological aspects of hypertension in kidney disease.
• Discussion of diagnostic modalities and therapeutic strategies.

Main Results:

• HT is a major contributor to adverse outcomes in CKD.
• Evidence supports new therapeutic targets for managing HT in CKD patients.
• Understanding the pathophysiology is key to effective management.

Conclusions:

• Systematic screening and optimal management of HT are essential for CKD patients.
• Clearer guidelines are needed to support general practitioners.
• Further research into novel therapeutic targets is warranted.