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Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

485
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
485
Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

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The aim of this study was to establish a standardized protocol for sleep endoscopy to differentiate obstruction patterns in obstructive sleep apnea (OSA). Target-controlled infusion (TCI) of the sedative was combined with real-time monitoring of the depth of sedation using bispectral...
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Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

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Here, we present experimental and analytical procedures to describe the temporal dynamics of the neural and cardiac variables of non-REM sleep in mice, which modulate sleep responsiveness to acoustic...
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Multi-Modal Home Sleep Monitoring in Older Adults07:40

Multi-Modal Home Sleep Monitoring in Older Adults

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Here, we present a protocol to improve the quality of data from home sleep testing by providing a method to enhance instructions through a structured participant visit. This protocol includes the implementation of a step-by-step educational manual with photos to ensure proper placement of...
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Quantitative Measurement of the Immune Response and Sleep in Drosophila12:16

Quantitative Measurement of the Immune Response and Sleep in Drosophila

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To understand a link between the immune response and behavior, we describe a method to measure locomotor behavior in Drosophila during bacterial infection as well as the ability of flies to mount an immune response by monitoring survival, bacterial load, and real-time activity of a key regulator of innate immunity,...
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Polygraphic Recording Procedure for Measuring Sleep in Mice

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The recording of electroencephalogram (EEG) and electromyogram (EMG) in freely behaving mice is a critical step to correlate behavior and physiology with sleep and wakefulness. The experimental protocol described herein provides a cable-based system for acquiring EEG and EMG recordings in...
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Related Experiment Video

Updated: Jan 19, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.5K

Sleep apnea and the heart.

Reena Mehra1

  • 1Sleep Disorders Research Program, Sleep Disorders Center, Neurological Institute, Cleveland Clinic mehrar@ccf.org.

Cleveland Clinic Journal of Medicine
|September 12, 2019
PubMed
Summary

Sleep apnea disrupts heart function, increasing risks for conditions like heart failure and stroke. Treatments can improve symptoms and quality of life, but definitive cardiovascular outcome data are pending.

Area of Science:

  • Cardiology
  • Sleep Medicine
  • Pulmonology

Background:

  • The normal sleep-wake cycle involves diurnal variations in cardiovascular function.
  • Sleep apnea, including obstructive sleep apnea (OSA) and central sleep apnea (CSA), disrupts the sleep-heart interaction.
  • Sleep-disordered breathing is linked to various cardiovascular diseases and mortality.

Purpose of the Study:

  • To review the associations between sleep apnea and cardiovascular diseases.
  • To discuss treatment options for sleep apnea and their impact on cardiovascular health.

Main Methods:

  • Review of existing literature on sleep apnea and cardiovascular outcomes.
  • Analysis of pathophysiology for OSA and CSA.
  • Evaluation of treatment effects on cardiovascular parameters and quality of life.

More Related Videos

Sleep Apnea
01:21

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485
Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

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Related Experiment Videos

Last Updated: Jan 19, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

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Sleep Apnea
01:21

Sleep Apnea

485
Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

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Main Results:

  • Sleep apnea is associated with heart failure, atrial fibrillation, stroke, coronary artery disease, and cardiovascular mortality.
  • Treatments like positive airway pressure, adaptive servo-ventilation, and phrenic nerve stimulation can improve blood pressure, quality of life, and sleepiness.
  • Clinical trial results are not yet definitive regarding hard cardiovascular outcomes.

Conclusions:

  • Sleep apnea significantly impacts cardiovascular health.
  • Current treatments offer symptomatic relief and improve certain cardiovascular markers.
  • Further research is needed to establish definitive cardiovascular outcome benefits of sleep apnea treatments.