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Updated: Jan 19, 2026

Cooperative Binding of Transcription Regulators
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Cooperative Silver Ion-Pair Recognition by Peralkylated Pillar[5]arenes

Bin Hua1, Li Shao1, Zhihua Zhang1

  • 1State Key Laboratory of Chemical Engineering, Center for Chemistry of High-Performance & Novel Materials, Department of Chemistry , Zhejiang University , Hangzhou 310027 , People's Republic of China.

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Transcriptional regulators bind to specific cis-regulatory sequences in the DNA to regulate gene transcription. These cis-regulatory sequences are very short, usually less than ten nucleotide pairs in length. The short length means that there is a high probability of the exact same sequence randomly occurring throughout the genome.  Since regulators can also bind to groups of similar sequences, this further increases the chances of random binding. Transcriptional regulators form...
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