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Updated: Jan 19, 2026

Measurement of Oxygen Consumption Rates in Intact Caenorhabditis elegans
Published on: February 23, 2019
The time course of adaptations in thermoneutral maximal oxygen consumption following heat acclimation
Mark Waldron1,2, O Jeffries3, J Tallent4
1College of Engineering, Swansea University, Swansea, UK. mark.waldron@swansea.ac.uk.
Purpose:
This study investigated the effects of a 10-day heat acclimation (HA) programme on the time course of changes in thermoneutral maximal oxygen uptake ([Formula: see text]O2max) during and up to 10 days post-HA.
Methods:
Twenty-two male cyclists were assigned to a HA or control (Con) training group following baseline ramp tests of thermoneutral [Formula: see text]O2max. Ten days of fixed-intensity (50% baseline [Formula: see text]O2max) indoor cycling was performed in either ~ 38.0 °C (HA) or ~ 20 °C (Con). [Formula: see text]O2max was re-tested on HA days 5, 10 and post-HA days 1, 2, 3, 4, 5 and 10.
Results:
[Formula: see text]O2max initially declined across time in both groups during training (P < 0.05), before increasing in the post-HA period in both groups (P < 0.05). However, [Formula: see text]O2max was higher than control by post-HA day 4 in the HA group (P = 0.046).
Conclusions:
The non-linear time course of [Formula: see text]O2max adaptation suggests that post-testing should be performed 96-h post-training to identify the maximal change for most individuals. In preparation for training or testing, athletes can augment their aerobic power in thermoneutral environments by performing 10 days HA, but the full effects will manifest at varying stages of the post-HA period.
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