[Oral liquid adult: age peculiarities of the physicochemical properties and micro crystallization.]

In 275 (69 men and 206 women) aged 25 to 86 years, including 74 elderly and old people suffering from type 2 diabetes mellitus, chronic nonspecific inflammatory bowel diseases, alcoholism, chronic kidney disease with the use of various laboratory methods, age-specific features of physical and chemical properties and microcrystallization of oral fluid were studied. It is shown that age-related changes in the composition and properties of mixed saliva and the peculiarities of its microcrystallization are due not only to the aging process, but also to concomitant chronic diseases. As you age, with a decrease in salivation in the oral fluid is determined by increasing the total protein content, reducing the Ca/P ratio, as well as increasing its viscosity. Age dynamics of microcrystallization of oral fluid in healthy adults was revealed. At young and middle age, types I and IIA of mixed saliva microcrystallization are more common at the length of the main axes of dendritic crystals of oral fluid equal, respectively, to 802,6±79,3 µm and 792,2±98,7 µm. In persons of older age groups without clear clinical manifestations of chronic diseases, IIB and IIC microcrystallization of oral fluid are more common with a decrease in the length of the main axes of dendritic crystals, respectively, to 618±77,3 µm and 581,4±69,9 µm. In the presence of clinically expressed psychosomatic pathology in elderly and senile people, the second and third types of microcrystallization of oral fluid are more common with a significant reduction in the length of the main axes of dendritic crystals of oral fluid to 413,2±94,6 µm.