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Updated: Jan 19, 2026

Enema of Traditional Chinese Medicine for Patients with Severe Acute Pancreatitis
Published on: January 27, 2023
Acute critically ill elderly patients: What about long term caregiver burden?
Hélène Vallet1, Laura Moïsi2, Caroline Thomas2
1Department of Geriatrics, Saint Antoine Hospital, Assistance Publique Hôpitaux de Paris (APHP), Paris, France; Sorbonne Université, Faculté de médecine, Paris, France; Institut National de la Santé et de la Recherche Médicale (INSERM), UMRS 1135, Centre d'immunologie et de Maladies Infectieuses (CIMI), Paris, France.
Purpose:
Acute critical illness induce a high caregivers burden in the young population, however data in the older population are lacking. The objectives of this study were to evaluate caregiver burden in a critically ill old population and to assess factors associated with mild to severe burden level.
Materials And Methods:
All patients from two participating centers of the ICE-CUB 2 trial were included in the study. Inclusion criteria were an age ≥75, at least one critical condition and preserved functional status. The primary endpoint was a Zarit Burden Interview (ZBI) ≥ 21 at 6 months.
Results:
One hundred ninety-one patients (median age 86 [81-89] years) were included. Median caregiver ZBI at 6 months was 13 [5-27]. In the multivariate analysis, factors significantly associated with moderate to severe burden were the 6-month ADL decrease (OR: 1.3, p = .049) and the 6-month mental component of the quality of life score (OR: 0.94, p = .0009). In contrast, age, ICU admission and length of hospital stay were not associated with moderate to severe load.
Conclusion:
In our study, functional status and mental health at 6 months were associated with mild to severe burden unlike age and admission in ICU.
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