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Updated: Jan 19, 2026

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
Published on: August 4, 2021
An 82-year-old man with recurrent angioedema
Charles F Schuler1, Elisabeth A Pedersen2, Marc S McMorris1
1From the Division of Allergy and Clinical Immunology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Recurrent angioedema, a serious swelling condition, can have various causes. This study presents a unique case where treating an underlying issue resolved the isolated recurrent angioedema.
Area of Science:
- Immunology
- Allergy and Clinical Immunology
- Dermatology
Background:
- Angioedema is a potentially life-threatening swelling, often recurrent, with diverse causes including histamine and bradykinin pathways.
- Differential diagnoses are broad, encompassing anaphylaxis, urticaria, medications, and complement deficiencies, yet often remain idiopathic.
- Effective treatment for recurrent angioedema can be challenging, particularly when the etiology is unclear.
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