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Updated: Jan 19, 2026

Methylene Blue Dye Injection in Mouse Embryonic Urinary Tract: A Method To Assess the Congenital Obstruction in the Urinary Tract
Interobserver Reliability of the Antenatal Consensus Classification System for Urinary Tract Dilatation
Caleb P Nelson1, Howard T Heller2, Carol B Benson2
1Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
The antenatal urinary tract dilatation (UTD) grading system demonstrated substantial interobserver agreement in prenatal ultrasounds. This UTD system showed better reader agreement than the Society for Fetal Urology (SFU) scoring method.
Area of Science:
- Medical Imaging
- Fetal Medicine
- Urology
Background:
- The urinary tract dilatation (UTD) classification system was developed for improved objectivity and reproducibility in diagnosing urinary tract issues.
- Previous systems for assessing urinary tract dilatation lacked consistent reliability among healthcare providers.
Purpose of the Study:
- To evaluate the interobserver reliability of the UTD classification system's components and overall scores.
- To compare the reliability of the UTD system with the Society for Fetal Urology (SFU) scoring system in a prenatal ultrasound setting.
Main Methods:
- Retrospective review of antenatal ultrasound images from 300 fetuses with urinary tract dilatation.
- Independent assessment of UTD and SFU scores by 5 experienced sonologists (1 maternal-fetal medicine specialist, 4 radiologists).
- Interobserver agreement was quantified using the Fleiss κ statistic.
Main Results:
- Substantial overall interobserver agreement was found for the antenatal UTD risk score (κ = 0.657).
- The UTD system exhibited better agreement among readers compared to the SFU system (κ = 0.368).
- Lowest agreement was observed for parenchymal appearance assessment within the UTD system (κ = 0.225).
Conclusions:
- The antenatal UTD grading system demonstrates substantial interobserver reliability.
- The UTD classification system offers improved diagnostic consistency in prenatal ultrasound evaluations compared to the SFU system.
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