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Updated: Jan 19, 2026

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
Published on: February 17, 2023
Insomnia and cognitive performance: A systematic review and meta-analysis
Sophie Wardle-Pinkston1, Danica C Slavish2, Daniel J Taylor1
1University of Arizona, Department of Psychology, Tucson, AZ, 85721, USA.
Insomnia negatively impacts cognitive functions, including attention, memory, and problem-solving. Treating insomnia may improve cognitive performance, but research methods need standardization.
Area of Science:
- Neuroscience
- Psychology
- Sleep Medicine
Background:
- Cognitive performance research in insomnia yields inconsistent results.
- A systematic review and meta-analysis are needed to synthesize existing literature.
Purpose of the Study:
- To systematically review and meta-analyze studies investigating the relationship between insomnia and cognitive performance.
- To identify specific cognitive domains affected by insomnia.
Main Methods:
- Conducted a systematic review and meta-analysis of 48 studies involving 4539 participants.
- Analyzed data using Hedge's g to quantify effect sizes across cognitive domains.
Main Results:
- Insomnia is associated with poorer overall cognitive performance (g = -0.24, p < 0.001).
- Specific impairments observed in subjective cognition, working memory, attention, alertness, episodic memory, and executive functions.
- No consistent moderation by age, gender, publication year, or insomnia measurement tools.
Conclusions:
- Insomnia is linked to objective and subjective cognitive deficits.
- Standardization of research methods for assessing insomnia and cognition is recommended.
- Treating insomnia may enhance cognitive outcomes.
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