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Updated: Jan 19, 2026
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Published on: October 26, 2016
Using a Composite Graft of Natural 15% Chitosan Gel in the Management of Intrabony Defects: A Case Series
Irfana Babrawala1, M L Prabhuji2, B V Karthikeyan1
1Department of Periodontology, Krishnadevaraya College of Dental Sciences and Hospital, Hunsmaranahalli, Bangalore 562157, India.
Introduction:
The purpose of this study was to compare effects of smoking and smokeless forms of tobacco consumption (tobacco chewing) on periodontal disease parameters and response of these subjects to non-surgical periodontal therapy.
Materials And Methods:
Ten patients aged between 30 and 55 years with intrabony defects greater than or equal to 3 mm and pocket probing depth (PPD) greater than or equal to 5 mm were selected. All participants received chitosan gel (15% w/v) plus bovine porous bone mineral as a composite bone graft. Clinical and radiographic measurements were recorded at baseline, 3 months after healing and at 6 and 9 months. Significance was set at 0.05.
Results:
After nine months, all the defects treated with this combination showed PPD reduction of 5.30 ± 0.822 mm, relative clinical attachment level (CAL) gain of 5.80 ± 0.499 mm, reduction in intrabony defect (IBD) depth of 3.00 ± 0.497 mm and defect resolution of 78.32 ± 5.80 %, all of which were statistically significant.
Conclusion:
Within the limits of this study, this case series study suggests that chitosan gel, along with bovine porous bone mineral, has a promising role to play in periodontal regeneration.
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