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Overprescribed Medications for US Adults: Four Major Examples.

Daniel J Safer¹

¹Departments of Psychiatry and Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

Journal of Clinical Medicine Research

|September 17, 2019

Summary

This summary is machine-generated.

Four common medication classes, including opioids and antidepressants, are frequently overprescribed to older adults for extended periods without clear benefits, contributing to polypharmacy concerns.

Keywords:

Antidepressants Levothyroxine Opioids Overmedicating Overprescribing Polypharmacy Proton pump inhibitors

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Area of Science:

Pharmacology
Geriatric Medicine
Health Services Research

Background:

Medication overprescribing is a growing concern, particularly among older adults.
Understanding prescription patterns for common drug classes is crucial for identifying potential overuse.

Purpose of the Study:

To evaluate overprescribing of four frequently prescribed medication classes in US adults.
To assess usage patterns, indications, duration, and benefit-risk profiles.

Main Methods:

Systematic review of the medical literature.
Analysis of prescription data for opioids, proton pump inhibitors, levothyroxine, and antidepressants.
Evaluation of usage trends, age groups, and treatment duration.

Main Results:

Four medication classes (opioids, PPIs, levothyroxine, antidepressants) show increased prescribing, especially in older adults.
These drugs are often prescribed for extended durations with inadequate evidence of benefit.
Polypharmacy and high drug usage patterns are linked to overprescribing in specific age groups.

Conclusions:

Overprescribing of common medications is prevalent, particularly in older populations.
Extended use of these medications often lacks sufficient evidence of efficacy.
Further research into medication usage patterns is needed to mitigate overprescribing and polypharmacy.