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Related Concept Videos

Aging01:26

Aging

617
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
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Continuous High-resolution Microscopic Observation of Replicative Aging in Budding Yeast10:41

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We describe here the operation of a microfluidic device that allows continuous and high-resolution microscopic imaging of single budding yeast cells during their complete replicative and/or chronological...
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The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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An Introduction to Aging and Regeneration09:14

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Tissues are maintained through a balance of cellular aging and regeneration. Aging refers to the gradual loss of cellular function, and regeneration is the repair of damaged tissue generally mediated by preexisting adult or somatic stem cells. Scientists are interested in understanding the biological mechanisms behind these two complex processes. By doing so, researchers may be able to use somatic stem cells to treat degenerative diseases and develop therapies that could delay the effects of...
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Behavioral Assessment of the Aging Mouse Vestibular System09:30

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Motor control and balance performance are known to deteriorate with age. This paper presents a number of standard noninvasive behavioral tests with the addition of a simple rotary stimulus to challenge the vestibular system and show changes in balance performance in a murine model of...
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Related Experiment Video

Updated: Jan 19, 2026

Continuous High-resolution Microscopic Observation of Replicative Aging in Budding Yeast
10:41

Continuous High-resolution Microscopic Observation of Replicative Aging in Budding Yeast

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Research Data Disclosure in the Digital Age.

Meghan K Mattos1, Jennifer H Lingler2

  • 1Acute and Specialty Care, University of Virginia School of Nursing, Charlottesville, VA, USA.

Journal of Alzheimer'S Disease : JAD
|September 17, 2019
PubMed
Summary

Digital advancements expand research but introduce ethical challenges. Protecting human subjects is paramount throughout data collection, management, and sharing in the Digital Age.

Keywords:
Data disclosuredata managementdata sharingecological momentary assessmentethicsresearch subjects

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Area of Science:

  • Digital Health
  • Research Ethics
  • Data Science

Background:

  • The Digital Age facilitates new research methodologies.
  • Traditional research models are expanding due to technological progress.
  • Increased data collection necessitates updated ethical frameworks.

Purpose of the Study:

  • To highlight ethical considerations in digital research.
  • To emphasize participant protection in data management and sharing.
  • To address the implications of big data in research.

Main Methods:

  • Review of current digital technologies in research.
  • Analysis of ethical challenges in data collection and sharing.
  • Examination of oversight requirements for human subjects.

Main Results:

  • Digital technologies offer expanded research capabilities.
  • New ethical considerations arise with data collection, management, and sharing.
  • Participant protection must be prioritized across the research continuum.

Conclusions:

  • Researchers, IRBs, and funding agencies must prioritize participant protection.
  • Big data and data sharing require significant investment and oversight.
  • Ensuring the ethical management and protection of human subjects is critical.