Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Inheritance on commissural lip pits].

F Zervou-Valvi, E Bazopoulou-Kyrkanidou

    Odontostomatologike Proodos
    |October 1, 1988
    PubMed
    Summary

    Commissural lip pits are a genetic disorder inherited in an autosomal dominant pattern. This study analyzed fifteen families, confirming the hereditary nature and variable expressivity of this condition.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Chimeric creatures in Greek mythology and reflections in science.

    American journal of medical genetics·2001
    Same author

    Epidermal nevus syndrome with development of a mandibular ameloblastoma.

    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics·2000
    Same author

    Growth retardation, distinct oriental-like facies, glaucoma, brachydactyly, ventricular septal defect and speech disorder. An unknown entity.

    Genetic counseling (Geneva, Switzerland)·1999
    Same author

    Alteration of integrin expression in oral squamous cell carcinomas.

    Oral diseases·1999
    Same author

    Hyalinosis cutis et mucosae: gingival involvement.

    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·1998
    Same author

    What makes Hephaestus lame?

    American journal of medical genetics·1997

    Area of Science:

    • Genetics
    • Medical Genetics
    • Human Genetics

    Context:

    • Commissural lip pits are congenital malformations affecting the corners of the mouth.
    • Understanding the inheritance pattern is crucial for genetic counseling and diagnosis.

    Purpose:

    • To investigate and determine the mode of inheritance for commissural lip pits.
    • To analyze clinical data and family pedigrees of affected individuals.

    Summary:

    • Fifteen families with commissural lip pits were studied, constructing detailed pedigrees.
    • Findings indicate autosomal dominant inheritance, with equal sex distribution and vertical transmission across generations.
    • Reduced penetrance and variable expressivity were observed, influencing trait manifestation.

    Impact:

    • Establishes a clear genetic basis for commissural lip pits, aiding in diagnosis and risk assessment.
    • Provides insights into the genetic mechanisms of congenital malformations.
    • Informs genetic counseling for families affected by commissural lip pits.

    Related Experiment Videos