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Updated: Jan 19, 2026

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
[The Brandenburg Network Healthy Children: Early Prevention Shows Effectiveness]
Gabriele Ellsäßer1, Hendrik Karpinski2, Annett Schmok3
1Landesamt für Arbeitsschutz Verbraucherschutz und Gesundheit, ehemals Leitung der Abteilung Gesundheit, Zossen.
Background And Aim Of The Study:
The Brandenburg Network Healthy Children (NHC) is a regional health programme for families with toddlers (0-3) run by trained volunteers. Based on the analysis of School Entry Medical Examination (SEME), the study investigates the possible influence of NHC on children's health.
Method:
A retrospective epidemiological analysis of the sociodemografic and health-related differences among subgroups nc and n-nc based on SEME, school year 2016/2017 (network children/nc: 1,152, not network children/n-nc: 20,954), using descriptive statistics; a logistic regression analysis assessing, for instance, the power of NHC's influence on health adjusting also for social status and region.
Results:
Parents with low/middle social status and one-parent families participated more frequently in the NHC (p<0.001). Nc compared to n-nc brought check-up documents (94.3 / 91.5%, p<0.001) and vaccination certificates (95.7 / 91.7%, p<0.001) more frequently to SEME. A higher tetanus-diphtheria-pertussis booster rate was observed after network participation. The adjusted model showed nc were less likely to have incomplete (U2-U6) check-ups (OR 0.347 [95%-KI: 0.192-0.627, p<0.001]), vaccination gaps (OR 0.621 [95%-KI: 0.508-0.758, p<0.001]) and more likely to be "optimally cared for" (OR 1.355 [95%-KI: 1.175-1.562, p<0.001]).
Conclusion:
Children's health showed benefit from network participation.
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