Related Experiment Video
Updated: Jan 19, 2026

Application of High-speed Super-resolution SPEED Microscopy in Live Primary Cilium
Published on: January 16, 2018
High-speed slot-scanning radiography using small-angle tomosynthesis: Investigation of spatial resolution
Christoph Luckner1,2, Magdalena Herbst2, Thomas Weber2
1Pattern Recognition Lab, Friedrich-Alexander University Erlangen-Nürnberg, Martensstraße 3, 91058, Erlangen, Germany.
Purpose:
This paper studies spatial resolution that is achievable with a fast slot-scanning tomosynthesis approach for orthopedic examinations. Hereby, we use parallel scanning motion implemented in a twin robotic x-ray system.
Methods:
We have measured and analyzed the modulation transfer function (MTF) for various combinations of scanning speed, x-ray tube voltage, pulse length, the nominal focal spot size as well as source-to-object distances. Moreover, we present a theoretical model which describes the system in terms of the MTF. The system was equipped with newly developed linear trajectory prototypes for slot scanning. The acquired images form the basis for a small-angle tomosynthesis reconstruction. In total, three different scanning speeds (27, 14, 8 cm/s), pulse lengths (1, 2, 4 ms), tube voltages (80, 100, 120 kV), two nominal focal spot sizes (0.6, 1.0), and three source-to-object distances (950, 1050, 1150 mm) were investigated. To determine the resolution capabilities, we measured the MTF for the given parameter space. The results were then used to design a filter that yields a desired resolution in the reconstructed image. In addition, we also measured the noise power spectrum (NPS) to show the influence of the aforementioned filters on the noise distribution.
Results:
We have shown that the presented model is in good agreement with the performed measurements. Scanning speed and pulse width have an impact on the MTF in the scanning direction. Up to a travel distance of 0.3 mm during an x-ray pulse, an isotropic resolution can be achieved. Longer pulse width or higher scanning speed cause anisotropic resolution. Moreover, it is shown that none of the investigated parameters have an influence on the MTF perpendicular to the scanning direction (slot direction). The 10% MTF value ranges between 9 and 18 lp/cm in the scanning direction and about 18 lp/cm in slot direction. Tube voltage, nominal focal spot size as well as the source-to-object distance showed no major impact on the system MTF. In terms of the anisotropic resolution capabilities, we have shown that limiting the resolution in the slot direction to obtain isotropic resolution is possible yet at the cost of an inhomogeneous noise pattern. However, maintaining the resolution in slot direction will provide a better edge response and a more homogeneous noise texture at the cost of an inhomogeneous image resolution.
Conclusions:
We have demonstrated the feasibility of the slot-scanning technique using a twin-robotic x-ray system. Even the fastest scanning mode (27 cm/s) yields image resolution on a level that is sufficient for typical orthopedic examinations in terms of musculoskeletal (MSK) measurements. Moreover, it could be shown that the application of specifically designed target MTFs on two-dimensional x-ray images is feasible.
More Related Videos
11:34High-resolution, High-speed, Three-dimensional Video Imaging with Digital Fringe Projection Techniques
Published on: December 3, 2013
10:24Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor
Published on: May 7, 2021
Related Concept Videos
07:53Application of High-speed Super-resolution SPEED Microscopy in Live Primary Cilium
11:34High-resolution, High-speed, Three-dimensional Video Imaging with Digital Fringe Projection Techniques
10:24Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor
08:41Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution
05:17Investigation of Spatial Interaction Between Astrocytes and Neurons in Cleared Brains
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...