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Updated: Jan 19, 2026

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
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Metal-Chelated Polymer Nanodiscs for NMR Studies

Nathaniel Z Hardin1, Vojč Kocman1, Giacomo M Di Mauro1

  • 1Biophysics Program and Department of Chemistry, University of Michigan, Ann Arbor, MI, 48109-1055, USA.

Angewandte Chemie (International Ed. in English)
|September 19, 2019
PubMed
Summary

Novel paramagnetic nanodiscs accelerate NMR data acquisition by reducing relaxation times. These functionalized nanodiscs offer enhanced structural insights for both lipid bilayers and water-soluble biomolecules like DNA G-quadruplexes.

Keywords:
NMR spectrocopyT1 enhancementmetal chelationparamagnetic relaxation enhancement (PRE)polymer nanodiscs

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