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Published on: November 25, 2025
Treatment of acute cholecystitis after cardiovascular surgery
Kimihiko Ueno1, Tetsuo Ajiki1, Daisuke Tsugawa1
1Department of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Insights
Acute cholecystitis after cardiovascular surgery often leads to gangrenous inflammation. Early surgical intervention is recommended, even for less severe cases, to improve outcomes for these complex patients.
Area of Science:
- Cardiovascular Surgery
- Gastrointestinal Surgery
- Postoperative Complications
Background:
- Acute cholecystitis (AC) following cardiovascular surgery (CS) is rare but associated with severe outcomes.
- Limited clinical data exists on AC after CS, necessitating further investigation.
Purpose of the Study:
- To investigate the clinical features of acute cholecystitis (AC) in patients who have undergone cardiovascular surgery (CS).
- To evaluate the severity, timing, surgical outcomes, and pathological findings of AC after CS.
Main Methods:
- Retrospective analysis of 26 patients who underwent surgery for AC after CS between 2001 and 2018.
- Evaluation of AC severity, onset, surgical outcomes, and pathological findings, compared to a control group.
Main Results:
- 46% of AC after CS cases were Grade III severity.
- AC after CS showed a higher rate of gangrenous cholecystitis (88%) and extended hospital stays compared to controls.
- The mortality rate for AC after CS was 12%.
Conclusions:
- Over 80% of AC after CS cases presented with gangrenous cholecystitis.
- Early surgical intervention for AC after CS, even Grade III, may be necessary due to the high rate of gangrenous changes.
Background:
Acute cholecystitis (AC) after cardiovascular surgery (CS) tends to have a serious postoperative course; however, there are few reports of AC after CS. In this study, we investigated the clinical features of AC after CS.
Method:
Of 26 patients who underwent surgery for AC after CS between 2001 and 2018 were investigated. Of these patients, the severity of AC, onset time, surgical outcomes, and postoperative pathological findings were evaluated.
Results:
Grade III accounted for 46% (12/26) of the AC after CS patients. Gallbladder drainage did not produce sufficient outcomes in all CS cases. The postoperative hospital days of AC after CS were extended (31/21 days, P = 0.07) and the postoperative pathologic findings revealed a higher rate of gangrenous cholecystitis (88/41%, P < 0.01) than the control group. With regard to the incidence of postoperative complications, there were no differences between CS and the control group (23/24%). The mortality rate of AC after CS was 12%.
Conclusion:
Because more than 80% of CS cases involved pathologically gangrenous cholecystitis, it may be necessary to perform early surgery for AC after CS, even when the severity of AC is Grade III.
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