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Dutch nOcturnal and hoME dialysis Study To Improve Clinical Outcomes (DOMESTICO): rationale and design
A van Eck van der Sluijs1, A A Bonenkamp2, F W Dekker3
1Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands.
BMC Nephrology
|September 20, 2019
Summary
Home dialysis offers an alternative to center-based treatment for End Stage Renal Disease patients. The DOMESTICO study compares home dialysis with in-center hemodialysis to assess quality of life, clinical outcomes, and costs.
Area of Science:
- Nephrology
- Clinical Outcomes Research
- Health Economics
Background:
- Over 6200 End Stage Renal Disease patients in the Netherlands rely on dialysis.
- In-center hemodialysis imposes a significant burden on patients due to frequent center visits.
- Limited data exists on the comparative effects of home dialysis versus in-center hemodialysis on patient quality of life, clinical outcomes, and healthcare costs.
Purpose of the Study:
- To prospectively investigate the impact of home dialysis therapies on health-related quality of life.
- To compare clinical outcomes and healthcare costs between home dialysis and in-center hemodialysis.
- To provide guidance for healthcare professionals and patients in shared decision-making regarding dialysis modality selection.
Main Methods:
- The Dutch nOcturnal and hoME dialysis Study To Improve Clinical Outcomes (DOMESTICO) is a nationwide, prospective, observational cohort study.
- 800 home dialysis patients (600 peritoneal dialysis, 200 home hemodialysis) and 800 in-center hemodialysis patients will be recruited over 3 years.
- Health-related quality of life, clinical outcomes, and costs will be measured every 3-6 months.
Main Results:
- This section is not available in the provided abstract.
Conclusions:
- The study aims to provide evidence to support shared decision-making for dialysis patients.
- Findings will help identify patient groups who may benefit most from home dialysis therapies.
- The research is expected to inform clinical practice and improve patient care in End Stage Renal Disease management.
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