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Updated: Jan 19, 2026

Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation
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Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation

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751

[Hyperpigmentation].

D Lipsker1, C Lenormand1

  • 1Clinique dermatologique des hôpitaux universitaires et faculté de médecine, Université de Strasbourg, 1, place de l'Hôpital, 67091 Strasbourg cedex, France.

Annales De Dermatologie Et De Venereologie
|September 21, 2019
PubMed
Summary
This summary is machine-generated.

Hyperpigmentation, a skin condition, can stem from melanin, iron, or carotene buildup. Diagnosis involves histopathology and lab tests, with treatments varying by cause.

Keywords:
Adrenal Cortical Tropic HormoneChloasmaCouleur de la peauHaemochromatosisHormone adrénocorticotropiqueHypermelanosisHypermélanoseHyperpigmentationHémochromatoseSkin

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Quantification of Hypopigmentation Activity In Vitro
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Area of Science:

  • Dermatology
  • Pathology

Background:

  • Hyperpigmentation involves excess melanin (hypermelanosis), iron (hemosiderosis), carotene (carotenoderma), or abnormal deposits (dyschromia).
  • Hypermelanosis can be localized (skin tumors, dermatoses) or generalized (systemic diseases, medications).

Purpose of the Study:

  • To review the diverse causes of hyperpigmentation.
  • To outline diagnostic approaches and therapeutic strategies for hyperpigmentation.

Main Methods:

  • Histopathology is the primary diagnostic tool.
  • Laboratory tests may supplement histopathological findings.

Main Results:

  • Hyperpigmentation etiologies include hypermelanosis, hemosiderosis, carotenoderma, and dyschromia.
  • Localized hypermelanosis is linked to skin tumors and dermatoses; generalized forms often indicate systemic metabolic or endocrine disorders.
  • Pharmaceuticals can also induce diffuse hyperpigmentation.

Conclusions:

  • Accurate diagnosis of hyperpigmentation relies on histopathology and relevant laboratory investigations.
  • Understanding the underlying cause is crucial for effective therapeutic management of hyperpigmentation.