Related Experiment Video
Updated: Jan 19, 2026

Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies
Published on: June 20, 2015
Innovative approaches for cancer treatment: current perspectives and new challenges
Carlotta Pucci1, Chiara Martinelli1, Gianni Ciofani1,2
1Smart Bio-Interfaces, Istituto Italiano di Tecnologia, 56025 Pisa, Italy.
Abstract:
Every year, cancer is responsible for millions of deaths worldwide and, even though much progress has been achieved in medicine, there are still many issues that must be addressed in order to improve cancer therapy. For this reason, oncological research is putting a lot of effort towards finding new and efficient therapies which can alleviate critical side effects caused by conventional treatments. Different technologies are currently under evaluation in clinical trials or have been already introduced into clinical practice. While nanomedicine is contributing to the development of biocompatible materials both for diagnostic and therapeutic purposes, bioengineering of extracellular vesicles and cells derived from patients has allowed designing ad hoc systems and univocal targeting strategies. In this review, we will provide an in-depth analysis of the most innovative advances in basic and applied cancer research.
Insights
This review explores innovative cancer research, focusing on nanomedicine and bioengineered therapies. These advanced approaches aim to improve cancer treatment efficacy and reduce side effects from conventional methods.
Area of Science:
- Oncology
- Biomedical Engineering
- Nanomedicine
Background:
- Cancer causes millions of deaths globally, necessitating improved therapies.
- Conventional cancer treatments have critical side effects.
- Ongoing research seeks novel and effective cancer treatments.
Purpose of the Study:
- To analyze innovative advances in basic and applied cancer research.
- To highlight the role of nanomedicine and bioengineering in cancer therapy.
- To discuss new diagnostic and therapeutic strategies.
Main Methods:
- Review of current clinical trials and practices.
- Analysis of nanomedicine applications in diagnostics and therapeutics.
- Evaluation of bioengineered extracellular vesicles and cells for targeted delivery.
Main Results:
- Nanomedicine offers biocompatible materials for cancer diagnosis and treatment.
- Bioengineered systems enable patient-derived cell and vesicle applications.
- Targeting strategies are being refined for enhanced efficacy.
Conclusions:
- Significant progress is being made in developing advanced cancer therapies.
- Nanomedicine and bioengineering represent promising frontiers in oncology.
- Innovative approaches are crucial for improving patient outcomes and reducing treatment burdens.
More Related Videos
07:32Author Spotlight: Investigating Immune Cell Dynamics in the Tumor Microenvironment — Challenges and Innovations in Cancer Prognosis
Published on: April 12, 2024
07:50Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
Related Concept Videos
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Targeted Cancer Therapies
There are several types of targeted therapies against...
Tumor Immunotherapy
Treatment Resistant Cancers
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...