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Related Concept Videos

Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

882
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
882
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

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Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
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Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

298
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
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Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
326
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

324
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

349
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Updated: Jan 19, 2026

Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development
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Continuous Renal Replacement Therapy in Preterm Infants.

Eu Seon Noh1, Hyun Ho Kim1, Hye Seon Kim1

  • 1Department of Pediatrics, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Korea.

Yonsei Medical Journal
|September 21, 2019
PubMed
Summary

Fluid overload is a key risk factor for mortality in preterm infants undergoing continuous renal replacement therapy (CRRT). Early CRRT initiation and fluid management are crucial for improving outcomes in these vulnerable neonates.

Keywords:
Continuous renal replacement therapyfluid overloadpremature infants

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Area of Science:

  • Neonatal Intensive Care
  • Pediatric Nephrology
  • Critical Care Medicine

Background:

  • Continuous renal replacement therapy (CRRT) use is increasing in neonatal intensive care units (NICUs).
  • Limited research exists on CRRT efficacy and outcomes in preterm infants.
  • Understanding prognostic factors is vital for this high-risk population.

Purpose of the Study:

  • To evaluate the prognosis of preterm infants treated with CRRT.
  • To identify mortality risk factors in preterm infants undergoing CRRT.

Main Methods:

  • Retrospective review of 33 preterm infants who received CRRT (2008-2017).
  • Collected data included demographics, comorbidities, cardiopulmonary function, and CRRT details.
  • Compared survivors and non-survivors using statistical analyses to find mortality predictors.

Main Results:

  • Non-survivors had lower gestational age, birth weight, and Apgar scores.
  • Non-survivors exhibited higher rates of inotropic use and fluid overload at CRRT initiation.
  • Fluid overload >10% at CRRT initiation was a significant predictor of mortality (aOR 14.6).

Conclusions:

  • Infant immaturity, cardiopulmonary instability, and fluid overload impact CRRT prognosis.
  • Preventing fluid overload and considering earlier CRRT initiation may enhance treatment outcomes.