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Vitreomacular interface alterations following peripheral laser retinopexy: Interface changes after laser.
Gian Marco Tosi1, Tommaso Bacci1, Antonio Tarantello1
1Ophthalmology Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Siena University Hospital, Siena, Italy.
European Journal of Ophthalmology
|September 21, 2019
Summary
Prophylactic peripheral laser retinopexy (PPLR) showed a 12.7% macular hole closure rate in the laser group, significantly higher than the non-laser group. This suggests PPLR may benefit selected patients with macular holes.
Area of Science:
- Ophthalmology
- Retinal Surgery
Background:
- Macular holes are a significant cause of vision loss.
- Surgical intervention is often required for treatment.
- The role of prophylactic treatments is under investigation.
Purpose of the Study:
- To evaluate the morphological outcomes of macular hole closure after prophylactic peripheral laser retinopexy (PPLR).
Main Methods:
- A retrospective case-control study involving 92 eyes.
- 55 eyes underwent PPLR before pars plana vitrectomy (laser group).
- 37 eyes did not undergo PPLR (non-laser group).
- Optical coherence tomography (OCT) assessed vitreomacular anatomy changes.
Main Results:
- Macular hole closure occurred in 7 of 55 eyes (12.7%) in the laser group versus 0 in the non-laser group (p < 0.05).
- Closure rates were higher in eyes with vitreomacular adhesion (33.3%) compared to those without (2.7%) in the laser group.
- Vitreomacular adhesion release rates were similar between groups (16.6% vs 7.6%, p > 0.05).
Conclusions:
- Prophylactic peripheral laser retinopexy may offer a beneficial role in selected macular hole patients.
- Further research is warranted to confirm these findings and optimize patient selection.

