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Nutraceutical Supplements in the Thyroid Setting: Health Benefits beyond Basic Nutrition
Salvatore Benvenga1,2,3, Ulla Feldt-Rasmussen4, Daniela Bonofiglio5
1Department of Clinical and Experimental Medicine-Endocrinology, University of Messina, via Consolare Valeria-Gazzi, 98125 Messina, Italy. s.benvenga@live.it.
Nutraceuticals show potential for thyroid health, but clinical data is limited. This review examines popular supplements like selenium and resveratrol, separating facts from myths regarding their use in thyroid disease.
Area of Science:
- Endocrinology
- Nutritional Science
- Pharmacology
Background:
- Growing interest in nutraceuticals for preventive and therapeutic applications in various diseases.
- Thyroid health relies on iodine, but other nutrients like selenium, l-carnitine, myo-inositol, melatonin, and resveratrol also play crucial roles.
- Some nutraceuticals possess antioxidant properties beneficial for overall health.
Purpose of the Study:
- To critically review the health benefits of popular nutraceutical supplements beyond basic nutrition.
- To focus on the effects of these nutraceuticals on thyroid pathophysiology.
- To differentiate established clinical evidence from misconceptions regarding nutraceutical use in thyroid disorders.
Main Methods:
- Comprehensive literature review of scientific articles and clinical studies.
- Critical analysis of research data on selected nutraceuticals and their impact on thyroid function.
- Evaluation of the quality and quantity of evidence supporting nutraceutical efficacy and safety.
Main Results:
- Identified several nutraceuticals (e.g., selenium, myo-inositol) with potential benefits for thyroid conditions.
- Highlighted the lack of robust clinical data and inconsistencies in supplement concentrations as major limitations.
- Distinguished between scientifically supported claims and unsubstantiated myths concerning nutraceuticals in thyroidology.
Conclusions:
- Nutraceuticals may offer adjunctive benefits in managing thyroid diseases, but require more rigorous clinical validation.
- Careful consideration of evidence and supplement quality is essential for appropriate use.
- Further research is needed to establish clear guidelines for nutraceutical application in thyroid care.
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