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Swine as models in experimental surgery.

M M Swindle1, A C Smith, B J Hepburn

  • 1Department of Comparative Medicine, Medical University of South Carolina, Charleston 29425.

Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research
|January 1, 1988
PubMed
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Correction.

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Swine are increasingly used in surgical research due to canine model scarcity and their suitable anatomy and physiology. This review covers key considerations for selecting and using pigs in experimental surgery.

Area of Science:

  • Veterinary Surgery
  • Comparative Medicine
  • Animal Models in Research

Background:

  • Growing demand for reliable animal models in surgical research.
  • Decreasing availability of traditional models like dogs.
  • Renewed scientific interest in porcine models due to anatomical and physiological similarities to humans.

Purpose of the Study:

  • To provide a comprehensive review of selecting swine for surgical research.
  • To outline critical factors for successful implementation of porcine models.
  • To guide researchers in utilizing swine effectively in experimental surgery.

Main Methods:

  • Review of current literature on swine procurement and handling.
  • Analysis of anesthetic protocols for porcine subjects.

Related Experiment Videos

  • Examination of housing requirements for experimental swine.
  • Compilation of relevant anatomical and physiological data for swine.
  • Main Results:

    • Swine offer significant advantages as surgical models.
    • Careful consideration of procurement, anesthesia, and housing is crucial.
    • Understanding swine anatomy and physiology is essential for successful research.

    Conclusions:

    • Swine represent a valuable and increasingly utilized model in surgical research.
    • Proper management and understanding of the animal are key to ethical and effective use.
    • Researchers must carefully weigh all factors when selecting swine for experimental procedures.