Related Experiment Video
Updated: Jan 19, 2026

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
Published on: May 26, 2023
Prolonged cardiopulmonary resuscitation and low flow state are not contraindications for extracorporeal support
Shriprasad R Deshpande1,2, Danish Vaiyani1, Angel R Cuadrado1
1Sibley Heart Center Cardiology, Children's Healthcare of Atlanta, Emory University, Atlanta, GA, USA.
Insights
Outcomes for pediatric out-of-hospital cardiac arrest remain poor. This case highlights the successful use of mechanical compression and extracorporeal cardiopulmonary resuscitation (ECPR) after prolonged resuscitation, improving survival.
Area of Science:
- Pediatric Critical Care Medicine
- Emergency Medicine
- Cardiology
Background:
- Out-of-hospital cardiac arrest (OHCA) in children has a dismal prognosis, with survival rates below 10%.
- Extracorporeal cardiopulmonary resuscitation (ECPR) is an emerging therapy to improve outcomes in select cases.
- Patient selection for ECPR is complex, influenced by arrest circumstances, resuscitation duration, and institutional resources.
Observation:
- We report a case of a pediatric patient experiencing an extremely prolonged out-of-hospital cardiac arrest.
- Mechanical chest compression devices were utilized during the extended resuscitation period.
- The patient was subsequently transitioned to extracorporeal membrane oxygenation (ECMO) for advanced circulatory and respiratory support.
Findings:
- This case demonstrates the potential utility of mechanical compression devices in prolonged resuscitation efforts.
- Successful transition to and utilization of ECMO following mechanical CPR in a pediatric OHCA patient.
- The case outcome offers insights into the management of refractory pediatric cardiac arrest.
Implications:
- This case may inform discussions on optimizing patient selection criteria for ECPR in pediatric refractory cardiac arrest.
- Further research is warranted to explore the role of mechanical circulatory support and ECPR in improving survival for pediatric OHCA.
- The findings encourage a broader consideration of advanced extracorporeal techniques in challenging pediatric resuscitation scenarios.
Abstract:
Outcomes of out-of-hospital cardiac arrest are poor irrespective of the patient age group and circumstances. Survival to discharge after out-of-hospital arrest in children is less than 10%. Use of extracorporeal cardiopulmonary resuscitation is increasing and has been shown to improve outcomes in some situations. However, the candidacy for such augmentation is based on patient selection, institutional practices, and availability of an extracorporeal membrane oxygenation center. Often, duration of resuscitation, low flow state, presenting pH, and circumstances of arrest dictate candidacy for extracorporeal membrane oxygenation. We present a case of extremely prolonged resuscitation for out-of-hospital arrest in a pediatric patient, and we describe the use of mechanical compression device and transition to extracorporeal membrane oxygenation. We present the case outcome as well as brief discussion about controversies in extracorporeal cardiopulmonary resuscitation. We hope the case provides an opportunity for further discussion regarding opportunities to improve selection, use of extracorporeal cardiopulmonary resuscitation, and impact outcomes.
More Related Videos
09:54Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
03:40Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
Published on: January 17, 2025
Related Concept Videos
Cardiopulmonary Resuscitation I: Adult
Cardiopulmonary Resuscitation IV: Pharmacological Management
Heart Failure VI: Adjunct Therapies