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Inducing apatite pre-layer on titanium surface through hydrothermal processing for osseointegration
E B Ansar1, K Ravikumar2, S Suresh Babu3
1Division of Bioceramics, Sree Chitra Tirunal Institute for Medical Sciences & Technology, 695012, India; Department of Chemistry, M.E.S Asmabi College, P. Vemballur, Kodungallur 680671, India.
Materials Science & Engineering. C, Materials for Biological Applications
|September 25, 2019
Summary
Researchers developed a novel nanolayer on titanium implants using a hydrothermal method. This calcium-enriched surface promotes early bone bonding and enhances osseointegration for improved dental implant stability.
Area of Science:
- Biomaterials Engineering
- Nanotechnology
- Dental Implantology
Background:
- Titanium (Ti) implants are vital for dental restoration due to their strength and biocompatibility.
- Current research focuses on nanoscale surface modifications for enhanced osseointegration.
- Achieving early implant stability is crucial for successful dental implantation.
Purpose of the Study:
- To develop a novel nanolayer nucleating agent on titanium implant surfaces.
- To investigate the bone bonding ability of calcium-modified titanium.
- To evaluate the potential for enhanced osseointegration and early stability of dental implants.
Main Methods:
- Titanium implants were surface-modified using calcium hydroxide (Ca(OH)2) via a hydrothermal technique (Ti-HT).
- Surface analysis included X-ray photoelectron spectroscopy (XPS) to confirm calcium incorporation as CaTiO3.
- In vitro studies involved simulated body fluid (SBF) immersion for apatite deposition assessment (SEM, XRD, FTIR, EDX) and cell viability assays (MTT).
Main Results:
- XPS confirmed the chemical bonding of Ca ions to the Ti surface, forming CaTiO3.
- Significant apatite deposition was observed on the Ti-HT surface after 7 days in SBF, indicating bone bonding ability.
- Cell viability assays showed no adverse effects, suggesting good biocompatibility of the modified surface.
Conclusions:
- The hydrothermal modification effectively created a calcium-enriched nanolayer on titanium implants.
- The Ca2+ ions on the Ti-HT surface promote apatite formation and enhance bone bonding.
- This novel surface treatment shows potential for improving osseointegration and achieving early stability in dental implants.
