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Inducing apatite pre-layer on titanium surface through hydrothermal processing for osseointegration.

E B Ansar1, K Ravikumar2, S Suresh Babu3

  • 1Division of Bioceramics, Sree Chitra Tirunal Institute for Medical Sciences & Technology, 695012, India; Department of Chemistry, M.E.S Asmabi College, P. Vemballur, Kodungallur 680671, India.

Materials Science & Engineering. C, Materials for Biological Applications
|September 25, 2019
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel nanolayer on titanium implants using a hydrothermal method. This calcium-enriched surface promotes early bone bonding and enhances osseointegration for improved dental implant stability.

Keywords:
BioactivityCalcium titanateEndosseousHydrothermal reactionTitanium implant

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Area of Science:

  • Biomaterials Engineering
  • Nanotechnology
  • Dental Implantology

Background:

  • Titanium (Ti) implants are vital for dental restoration due to their strength and biocompatibility.
  • Current research focuses on nanoscale surface modifications for enhanced osseointegration.
  • Achieving early implant stability is crucial for successful dental implantation.

Purpose of the Study:

  • To develop a novel nanolayer nucleating agent on titanium implant surfaces.
  • To investigate the bone bonding ability of calcium-modified titanium.
  • To evaluate the potential for enhanced osseointegration and early stability of dental implants.

Main Methods:

  • Titanium implants were surface-modified using calcium hydroxide (Ca(OH)2) via a hydrothermal technique (Ti-HT).
  • Surface analysis included X-ray photoelectron spectroscopy (XPS) to confirm calcium incorporation as CaTiO3.
  • In vitro studies involved simulated body fluid (SBF) immersion for apatite deposition assessment (SEM, XRD, FTIR, EDX) and cell viability assays (MTT).

Main Results:

  • XPS confirmed the chemical bonding of Ca ions to the Ti surface, forming CaTiO3.
  • Significant apatite deposition was observed on the Ti-HT surface after 7 days in SBF, indicating bone bonding ability.
  • Cell viability assays showed no adverse effects, suggesting good biocompatibility of the modified surface.

Conclusions:

  • The hydrothermal modification effectively created a calcium-enriched nanolayer on titanium implants.
  • The Ca2+ ions on the Ti-HT surface promote apatite formation and enhance bone bonding.
  • This novel surface treatment shows potential for improving osseointegration and achieving early stability in dental implants.